Синтез и изучение свойств липодипептидов для самоорганизующихся систем доставки функциональных генов тема диссертации и автореферата по ВАК РФ 02.00.10, кандидат химических наук Буданова, Ульяна Александровна

• Буданова, Ульяна Александровна
• кандидат химических наук
• 2008

Оглавление диссертации кандидат химических наук Буданова, Ульяна Александровна

СПИСОК ПРИНЯТЫХ В РАБОТЕ СОКРАЩЕНИЙ.

ВВЕДЕНИЕ.

ЛИТЕРАТУРНЫЙ ОБЗОР.

Компоненты катионных липосом.

Комплекс амфифил/ДНК.

Средства для модификации липосом.

Включение в липосомы векторов активного нацеливания на клетку-мишень.

Контролируемое высвобождение содержимого липосом.

РЕЗУЛЬТАТЫ РАБОТЫ И ИХ ОБСУЖДЕНИЕ.

Синтез липодипептидов на основе эфиров /,-глутаминовой кислоты и /,-глутамина.

Исследование свойств агрегатов, формируемых полученными соединениями в водной среде.

Изучение свойств комплексов катионные липодипептиды/ДНК.

Определение эффективности трансфекции полученных соединений.

ВЫВОДЫ.

ЭКСПЕРИМЕНТАЛЬНАЯ ЧАСТЬ.

Список литературы диссертационного исследования кандидат химических наук Буданова, Ульяна Александровна, 2008 год

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