Прогноз, профилактика и лечение осложнений транслюминальных коронарных вмешательств у больных ишемической болезнью сердца тема диссертации и автореферата по ВАК РФ 14.00.06, доктор медицинских наук Першуков, Игорь Викторович

• Першуков, Игорь Викторович
• доктор медицинских наук
• 2004

Оглавление диссертации доктор медицинских наук Першуков, Игорь Викторович

Список сокращений.

Введение.

Глава 1. Обзор литературы.

1.1 Развитие ЧТКВ в лечении ишемической болезни сердца.

1.2 Механизм ЧТКВ.

1.3 Непосредственные и ближайшие результаты ЧТКВ.

1.4 Отдаленные результаты ЧТКВ.

1.5 Рестеноз после коронарного стентирования.

Введение диссертации (часть автореферата) на тему «Прогноз, профилактика и лечение осложнений транслюминальных коронарных вмешательств у больных ишемической болезнью сердца»

Чрезкожные транслюминальные коронарные вмешательства (ЧТКВ) применяются в клинической практике с конца 70-х годов XX века. Проведенные ранее исследования показали высокую эффективность ЧТКВ в лечении стенозирующих поражений коронарных артерий у больных ИБС [9]. Малая травматичность, отсутствие наркоза, снижение затрат и другие преимущества позволили ЧТКВ опередить операции аортокоронарного шунтирования и другие методы прямой реваскуляризации миокарда [509]. В США и многих странах Европы соотношение ЧТКВ и операций АКШ составляет 1.5-2:1 [6,9,52]. Количество ЧТКВ в развитых странах продолжает увеличиваться.

Широкое распространение ЧТКВ выявило отрицательные стороны их применения. Наиболее грозными острыми осложнениями ЧТКВ оказались выраженная диссекция сосуда, его полная окклюзия и дистальная эмболизация. В начале применения ЧТКВ окклюзия возникала в 5-7% случаев, приводя зачастую к инфаркту миокарда и летальному исходу [152]. К настоящему времени в разных лабораториях острые фатальные и нефатальные осложнения ЧТКВ отмечаются в 1-2% случаев [623]. Но анализ причин осложнений, как правило, затруднен, поскольку во многих российских катетерных лабораториях пока выполняется не более 400 вмешательств в год и статистика 5-10 ежегодных осложнений не позволяет делать каких-либо достоверных выводов [5].

В отдаленном периоде повторное сужение сосуда (рестеноз) стало «Ахиллесовой пятой» баллонных методов лечения. На первых порах рестеноз развивался в 30-60% случаев в течение 6 месяцев после ЧТКВ [111]. После внедрения в 90-х годах коронарных стентов частота рестеноза снизилась на 10-20% [83]. Но повторное сужение внутри стента оказалось процессом, отличающимся по своей морфологии от рестеноза после обычной баллонной дилатации, и потребовало новых подходов к его профилактике и лечению [88].

До настоящего времени не создано абсолютно эффективного метода профилактики рестеноза после баллонной ангиопластики и коронарного стентирования. Распространению локальной радиации или «брахитерапии», достоверно уменьшающей на 30-60% частоту рестеноза и применяемой для первичной и вторичной профилактики, препятствует сложность доставки и хранения радиоактивных инструментов [660,707,711,712]. Покрытые антирестенотическими препаратами (сиролимус и таксол) стенты достоверно снижают частоту повторных сужений в популяции с 15-45% до 4-8% [405,470,631]. Но стоимость покрытых лекарственными препаратами стентов выше непокрытых устройств в 2,5-3 раза, что значительно увеличивает затраты, и пока не позволяет широко применять покрытые стенты. К тому же развитие подострого тромбоза и внезапной смерти в течение нескольких месяцев после имплантации покрытого стента за последний год стало проблемой на пути применения покрытых стентов в реальной клинической практике. Потому многие инвазивные кардиологи продолжают имплантировать непокрытые стенты, а в случае развития рестеноза внутри стента проводят обычную баллонную ангиопластику, получая повторное сужение в 20-80% случаев [450]. В то же время применение экстракционных методов, в частности эксимерной лазерной ангиопластики, перед баллонной дилатацией или повторным стентированием рестеноза внутри стента позволило снизить частоту осложнений [230]. К сожалению, отдаленные результаты лазерной ангиопластики при рестенозе внутри стента пока мало изучены. Также считают [587], что повторное стентирование при рестенозе внутри стента может улучшить непосредственный результат, но до настоящего времени в литературе немного данных о повторном рестенозировании в стенте и эффективности такого лечения поражений внутри стента. Целью исследования является выявление факторов, связанных с развитием ближайших и отдаленных осложнений ЧТКВ, а также сравнительная оценка эффективности и безопасности различных транслюминальных методов лечения и вторичной профилактики рестеноза в стенте. Задачи исследования:

1. Изучить частоту внезапного закрытия сосуда во время и после транслюминальных коронарных вмешательств, выявить клинические, ангиографические и процедурные факторы, связанные с развитием внезапного закрытия сосуда;

2. Проанализировать отдаленные до 6 месяцев результаты коронарного стентирования, выявить клинические, ангиографические и процедурные факторы, влияющие на развитие диффузной и агрессивной форм рестеноза внутри стента;

3. Сравнить непосредственные и госпитальные результаты баллонной ангиопластики и лазерной ангиопластики в лечении рестеноза внутри стента;

4. Проанализировать отдаленные до 6 месяцев исходы баллонной ангиопластики и лазерной ангиопластики у больных с рестенозом внутри стента;

5. Оценить непосредственные и госпитальные результаты повторного коронарного стентирования у больных с рестенозом внутри стента;

6. Изучить отдаленные до 6 месяцев исходы повторного коронарного стентирования у больных с рестенозом внутри стента;

7. Сопоставить безопасность и эффективность баллонной, лазерной ангиопластики и повторного коронарного рестентирования в лечении рестеноза внутри стента по госпитальным данным и результатам отдаленных наблюдений.

Научная новизна:

Впервые из репрезентативной выборки 10439 больных с ИБС, перенесших чрезкожное транслюминальное коронарное вмешательство, выделены 885 пациентов, у которых случалось наиболее грозное острое осложнение - внезапное закрытие сосуда, выявлены клинические, ангиографические и процедурные факторы, значимо связанные в реальной клинической практике с развитием внезапной окклюзии.

В группе 456 больных, перенесших коронарное стентирование без острых осложнений, установлены значимые признаки, связанные с развитием диффузной и агрессивной форм рестеноза в стенте.

У 190 больных с рестенозом в стенте проведена сравнительная оценка трех наиболее распространенных эндоваскулярных методов лечения рестеноза: баллонной ангиопластики, лазерной ангиопластики и повторного коронарного стентирования. Результаты лечения рестеноза в стенте прослежены на протяжении более 6 месяцев. Практическая значимость:

Показано, что плановое коронарное стентирование является единственным процедурным фактором, значимо снижающим риск внезапного закрытия сосуда в ходе ЧТКВ.

Являясь наиболее часто применяемым методом ЧТКВ, коронарное стентирование приводит к рестенозу, причем среди больных с рестенозом внутри стента у 63% процесс рестеноза является диффузным и превышает

10 мм. Наиболее часто рестеноз в стенте развивается у женщин и больных сахарным диабетом. При лечении РВС непосредственный успех ТБКА, ЭЛКА и коронарного стентирования был сопоставимым: 98.3%, 98.5% и 100% соответственно.

Несмотря на большую сложность в выполнении повторного стентирования при РВС, его отдаленный исход оказался благоприятнее исхода после ЭЛКА (выживаемость без сердечно-сосудистых осложнений за 8 месяцев - 84% против 62.3%) и лучше исхода после ТБКА (выживаемость без сердечно-сосудистых осложнений - 53.6%). Поэтому повторное коронарное стентирование является методом выбора среди ЧТКВ у пациентов с РВС.

Заключение диссертации по теме «Кардиология», Першуков, Игорь Викторович

выводы.

У больных, перенесших чрезкожное транслюминальное коронарное вмешательство, в госпитальном периоде возникает внезапное закрытие сосуда в 4-16% в зависимости от ряда факторов и их комбинаций. Частота внезапного закрытия сосуда наиболее значимо коррелирует с исходными рентгеноморфологическими характеристиками поражения: эксцентричностью, изъязвлением, кальцинозом, тромбозом бляшки, извитостью артерии, а также с курением.

Риск внезапного закрытия увеличивается при неотложных коронарных вмешательствах: у больных с нестабильной стенокардией (ОШ=2.13), с острым инфарктом миокарда (ОШ=2.76), особенно осложненным кардиогенным шоком (0111=4.31). Риск внезапного закрытия сосуда меньше при плановом стентировании (0111=0.43) и больше при неотложном стентировании (0111=1.45), обычной баллонной ангиопластике (ОШ=1.66) и реолитической тромбэкстракции (0111=1.95).

Прогноз осложнений после транслюминального коронарного вмешательства у больных ишемической болезнью сердца зависит от рентгеноморфологического типа поражения коронарного русла, опыта оперирующего врача и характера проводимой антиагрегантной терапии.

5. Непосредственный успех коронарного стентирования составляет 9699% по сравнению с 84-92% после обычной баллонной ангиопластики. В течение полугода рестеноз развивается у 25-40% больных после коронарного стентирования по сравнению с 35-50% рестеноза после обычной баллонной ангиопластики.

6. По характеру поражения рестеноз внутри стента в 37%) является локальным, а в 63% - диффузным, в том числе у 18% приводит к полной окклюзии просвета артерии.

7. Диффузный и агрессивный рестеноз внутри стента чаще развиваются у больных сахарным диабетом и женщин.

8. Рентгеноморфологическими предпосылками для диффузного рестеноза внутри стента являются малый минимальный диаметр сосуда и малый должный диаметр сосуда, а для агрессивного рестеноза в стенте -больший минимальный диаметр сосуда и малая длина исходного поражения.

9. Имплантация проволочного стента приводит чаще к диффузному и агрессивному рестенозу внутри стента.

10. Непосредственный положительный результат лечения рестеноза внутри стента при выполнении только баллонной ангиопластики составляет 98.3%, при комбинации лазерной и баллонной ангиопластики - 98.5%, а при повторном стентировании - 100%.

11. Частота госпитальных осложнений после лечения рестеноза внутри стента при баллонной ангиопластике составляет 8.6%, при комбинации лазерной и баллонной ангиопластики 3.0%, а при повторном стентировании 5.0%.

12. Через 6 месяцев кумулятивная частота сердечно-сосудистых осложнений была минимальной после повторного стентирования рестеноза внутри стента - 18%, после комбинации баллонной и лазерной ангиопластики составила 37% и максимальна после обычной баллонной ангиопластики - 46%.

13. Сравнение госпитальных и отдаленных результатов трех эндоваскулярных методов воздействия на рестеноз внутри стента показало, что наиболее эффективным и безопасным методом является повторное коронарное стентирование («стент в стент»).

14. Прогноз осложнений после эндоваскулярного лечения рестеноза внутри стента зависит от рентгеноморфологического типа поражения в стенте и выбранного эндоваскулярного метода воздействия на рестеноз.

ПРАКТИЧЕСКИЕ РЕКОМЕНДАЦИИ.

1. У больных ИБС при планирования инвазивного вмешательства для уменьшения риска внезапного закрытия сосуда методом выбора является коронарное стентирование.

2. Для первичной профилактики рестеноза внутри стента оптимально выполнять процедуру стентирования при большем должном диаметре сосуда и применять по возможности короткие матричные стенты.

3. При лечении рестеноза внутри стента повторное стентирование является методом выбора. Баллонную ангиопластику и лазерную ангиопластику целесообразно выполнять при исходных технических сложностях для имплантации второго стента.

Список литературы диссертационного исследования доктор медицинских наук Першуков, Игорь Викторович, 2004 год

1. Абугов С.А. Баллонная коронарная ангиопластика у больных ишемической болезнью сердца с неблагоприятными морфологическими и клиническими особенностями. // Автореф. дисс. докт. Москва 1998; 47с.

2. Абугов С.А., Пурецкий М.В., Руденко Б.А., и др. Результаты эндоваскулярного стентирования бифуркационных стенозов у больных ишемической болезнью сердца. //Кардиология 1998;8:7.

3. Аронов Д.М., Лупанов В.П., Михеева Т.Г. Функциональные пробы в кардиологии: Электрографический контроль при функциональных пробах. //Кардиология 1995;12:83-93.

4. Афифи А., Эйзен С. Статистический анализ: подход с использованием ЭВМ. // Пер. с англ. М. Мир 1982; 488с.

5. Бабунашвили A.M., Иванов В.А. Применение коронарного стентирования в зависимости от клинической картины ИБС и типа атеросклеротического поражения коронарного русла. // Москва 2000; 77с.

6. Бабунашвили A.M., Иванов В.А., Бирюков С.А. Эндопротезирование (стентирование) венечных артерий сердца. // Москва 2000; 704 с.

7. Бабунашвили A.M., Рабкин И.Х., Иванов В.А. Коронарная ангиопластика. //Москва 1996; 352с.

8. Бакланов Д.В., Мэзден P.P. Коронарная ангиопластика. // Санкт-Петербург 1996; 104с.

9. Батыралиев Т.А., Беленков Ю.Н. Инвазивная кардиология -возможности и перспективы. // Кардиология 2001;9:4-10.

10. Болезни сердца и сосудов. Под ред. Е. И. Чазова в 4-х томах. // Москва 1992;т.2:509с.

11. П.Боровиков В.П. STATISTICA. Искусство анализа данных на компьютере: Для профессионалов. // 2-е изд. СПб. Питер 2003;688с.

12. Власов В.В. Введение в доказательную медицину. // М., Медиасфера 2001 ;392с.

13. Гланц С. Медико-биологическая статистика. // Пер. с англ. М. Практика 1999; 459с.

14. Н.Гогин Е.Е. Гипертоническая болезнь. // М. 1997; 335с.

15. Грацианский Н.А. К выходу рекомендаций Всероссийского научного общества кардиологов «Лечение острого коронарного синдрома без стойких подъемов сегмента ST на ЭКГ». // Кардиология 2002; 1:4-14.

16. Грацианский Н.А. Клопидогрель следует добавлять к аспирину по крайней мере на год после чрескожных коронарных вмешательств (CREDO), а перед ними можно применять и в дозе 600 мг (ISAR-COOL). // Кардиология 2003;5:71-73.

17. Иберла К. Факторный анализ. // М. Статистика 1980; 398с.

18. Интервенционные методы лечения ишемической болезни сердца. Под ред. Л.А.Бокерия, Б.Г.Алекяна, А.Коломбо, Ю.И.Бузиашвили. // Изд-во НЦССХ им.А.Н.Бакулева РАМН Москва 2002; 417с.

19. Козлов К.Л. Интервенционная пластика венечных артерий. // Санкт-Петербург ЭЛБИ 2000; 230с.

20. Крамер Г. Математические методы статистики. // Пер. с англ. М. Мир 1975; 648с.21 .Крыжановский В.А. Диагностика и лечение инфаркта миокарда. // Киев ФЕНИКС 2001; 451с.

21. Левицкий И.В. Сравнительная оценка методов и систем количественного коронарного анализа и их клинического применения. // Автореф. дисс. канд. Москва 2000; 22с.

22. Панченко Е.П., Добровольский А.Б. Тромбозы в кардиологии. Механизмы развития и возможности терапии. // М. «Спорт и культура» 1999; 464с.

23. Рабкин И.Х., Абугов В.М., Старикова В.Б. и соавт. Первый опыт и возможности рентгеноэндоваскулярной дилатации стенозов коронарных артерий. //Кардиология 1983;6:17-21.

24. Реброва О.Ю. Статистический анализ медицинских данных. Применение пакета прикладных программ STATISTICA. // М., Медиасфера 2002;312с.

25. Роган С.В., Араблинский А.В., Соловьев О.П. Тромбоз стента у пациентов с острым инфарктом миокарда. // Кардиология 2003;2:77-81.

26. Савченко А.П., Абугов А.А., Смирнов А.А. и соавт. Результаты баллонной коронарной ангиопластики коронарных артерий у больных пожилого возраста. // Визуализация в клинике 1992;1:5-8.

27. Самко А.Н. Применение интракоронарных стентов для лечения больных ишемической болезнью сердца. // Русский мед. журнал 1998;т.6;№14:21-24.

28. Самко А.Н., Савченко А.П. Некоторые современные направления чреспросветной коронарной ангиопластики. // Кардиология 1993;9:62-67.

29. Сидоренко Б.А., Преображенский Д.В. Клиническое применение антитромботических препаратов. // Москва 1997; 178с.

30. Тюрин Ю.Н., Макаров А.А. Статистический анализ данных на компьютере. // Под ред В.Э.Фигурнова М. ИНФРА-М 1998;528с.

31. Флетчер Р., Флетчер С., Вагнер Э. Клиническая эпидемиология. Основы доказательной медицины. // Пер. с англ. М. Медиасфера 1998;352с.

32. Шахнович А., Шатц Р.А. Расширяемые баллонные стенты Пальмац-Шатц для коронарного протезирования. // Johnson & Johnson Interventional Systems Co 1996; 59c.

33. Янус B.M. Эффективность внутрипросветной баллонной ангиопластики коронарных артерий при ишемической болезни сердца. // Автореф. дисс. канд. М. 1989.

34. Abbo, et al. Features and outcomes of no-reflow after percutaneous coronary interventions. // Am J Cardiol 1995;75; 12:778-82.

35. Abdelmeguid AE, Whitlow PL, Sapp SK, et al. Long-term outcome of transient uncomplicated in-laboratory coronary artery closure. // Circulation 1995;91:2722-41.

36. Abizaid A, Kornowski R, Mintz GS, et al. The influence of diabetes mellitus on acute and late outcomes following coronary stent implantation. // J Am Coll Cardiol 1998;32:584-9.

37. Abizaid AA, Munoz JS, Seixas AC, et al. Is there any arterial toxic effect after overlapping sirolimus-eluting stents? // J Am Coll Cardiol. 2003;41(Suppl A):13A.

38. Abizaid AS, Mehran R, Mintz GS, et al. Impact of diabetes on coronary remodeling in patients with acute coronary syndromes: an intravascular ultrasound study. J Am Coll Cardiol. 2003;41(Suppl A):8A. Abstract 1007197.

39. Adamian M, Colombo A, Briguori C, et al. Cutting balloon angioplasty for the treatment of in-stent restenosis: a matched comparison with rotational atherectomy, additional stent implantation and balloon angioplasty. // J Am Coll Cardiol 2001;38:672-9.

40. Adelman AG, Cohen EA, Kimball BP, et al. A comparison of directional atherectomy with balloon angioplasty for lesions of the left anterior descending coronary artery. // N Engl J Med 1993;329:228-33.

41. Ahmed JM, Mintz GS, Waksman R, et al. Serial intravascular ultrasound analysis of the impact of lesion length on the efficacy of intracoronary gamma irradiation for preventing recurrent in-stent restenosis. // Circulation 2001;103:188-91.

42. Ahmed WH, Bittl JA, Braunwald E. Relation between clinical presentation and angiographic findings in unstable angina pectoris, and comparison with that in stable angina. // Am J Cardiol 1993;72:544-550.

43. Airoldi F, DiMario C, Stankovic G, et al. Estradiol eluting stents for the prevention of restenosis in native coronary arteries: results from the randomized multicentric study EASTER. J Am Coll Cardiol. 2003;41(Suppl A):56A.

44. Ajani A, Kim H-S, Waksman R. Clinical trials of vascular brachytherapy for in-stent restenosis: update. // Cardiovasc Radiat Med 2001;2:107-13.

45. Akiyama T, Moussa I, Reimers B, et al. Angiographic and clinical outcome following coronary stenting of small vessels: a comparison with coronary stenting of large vessels. // J Am Coll Cardiol 1998;32;6:1610-8

46. Ako J, Morino Y, Honda Y, et al. Late incomplete stent apposition following sirolimus eluting stent: serial quantitative intravascular ultrasound analysis from the SIRIUS trial. J Am Coll Cardiol. 2003;41(Suppl A):33A.

47. Al Suwaidi J, Berger P, Holmes DR. Coronary artery stents. // JAMA 2000;284:1828-36.

48. Albiero R, Adamian M, Kobayashi N, et al. Short and intermediate term results of 32P radioactive beta-emitting stent implantation in patients with coronary artery disease. // Circulation 2000; 101:18-26.

49. Albiero R, Nishida T, Karvouni E, et al. Cutting balloon angioplasty for the treatment of in-stent restenosis. // Cathet Cardiovasc Diagn 2000;50:452-9.

50. Alfonso F, Cequier A, Zueco J, et al. Stenting the stent: initial results and long-term clinical and angiographic outcome of coronary stenting for patients with in-stent restenosis. // Am J Cardiol 2000;85:327-32.

51. Alfonso F, Fernandez-Ortiz A, Goicolea J, et al. Angioscopic evaluation of angiographically complex coronary lesions. // Am Heart J 1997;134:703-711.

52. Alfonso F, Goicolea J, Hernandez R, et al. Angioscopic findings during coronary angioplasty of coronary occlusions. // J Am Coll Cardiol 1995;26:135-141.

53. Alfonso F, Gomez-Recio M, Cequier A, et al. Final angiographic results of the restenosis intra-stent: balloon angioplasty versus elective stenting (RIBS) randomised study. // Eur Heart J 2001;22:1264A.

54. Alfonso F, Hernandez R, Goicolea J, et al. Coronary stenting for acute coronary dissection after coronary angioplasty: implications of residual dissection. // J Am Coll Cardiol 1994;24:989 -995.

55. Alfonso F, Macaya C, Goicolea J, et al. Intravascular ultrasound imaging of angiographically normal coronary segments in patients with coronary artery disease. // Am Heart J 1994;127:536-544.

56. Alfonso F, Macaya C, Iniguez A, et al. Percutaneous coronary angioplasty after non-Q-wave acute myocardial infarction. // Am J Cardiol 1990;65:835-839.

57. Alfonso F, Perez-Vizcayno MJ, Hernandez R, et al. Long-term outcome and determinants of event-free survival in patients treated with balloon angioplasty for in-stent restenosis. // Am J Cardiol 1999;83:1268-1270.

58. Alfonso F, Zueco J, Cequer A, et al. A randomized comparison of repeat stenting with balloon angioplasty in patients with in-stent restenosis. // J Am Coll Cardiol 2003;42:796-805.

59. Alt E, Haehnel I, Beilharz C, et al. Inhibition of neointima formation after experimental coronary stenting. // Circulation 2000;101:1453-8.

60. Amant C, Bauters C, Bodart JC, et al. D allele of the angiotensin I-converting enzyme is a major risk factor for restenosis after coronary stenting. // Circulation 1997;96; 1:56-60.

61. Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci 1998;54:1175-202.

62. Ambrose JA, Winters SL, Arora RR, et al. Coronary angiographic morphology in myocardial infarction: a link between the pathogenesis of unstable angina and myocardial infarction. // J Am Coll Cardiol 1985;6:1233-1238.

63. Ambrose JA, Winters SL, Stern A, et al. Angiographic morphology and the pathogenesis of unstable angina pectoris. // J Am Coll Cardiol 1985;5:609-616.

64. Ambrose JA. Thrombolysis as an adjunct to angioplasty. // Am J Cardiol 1993;72:34G-9G.

65. Amols Ш, Zaider M, Weinberger J, et al. Dosimetric considerations for catheter-based beta and gamma emitters in the therapy of neointimal hyperplasia in human coronary arteries. // Int J Radiat Oncol Biol Phys 1996;36:913-21.

66. Amplatz K, Formanek G, Stranger P, Wilson W. Mechanics of selective coronary artery catheterization via femoral approach. // Radiology 1967;89:1040-7.

67. Anderson HV, Kirkeeide RL, Willerson JT, et al. Coronary artery flow monitoring: the value of intravascular Doppler for detection of complications after interventions. // Eur Heart J 1995;16:93-6.

68. Anderson HV, Revana M, Rosales O, et al. Intravenous administration of monoclonal antibody to the platelet GP Ilb/IIIa receptor to treat abrupt closure during coronary angioplasty. // Am J Cardiol 1992;69:1373-6.

69. Annest LS, Anderson RP, Li W, Haferamnn MD. Coronary artery disease following mediastinal radiation therapy. // J Thorac Cardiovasc Surg 1983;85:257-63.

70. Appelman YEA, Piek JJ, Redekop WK, et al. Excimer laser coronary angioplasty versus balloon angioplasty in long coronary lesions: a multivariate analysis. // Eur Heart J 1995; 16:487.

71. Aubry P, Royer T, Spaulding C, et al. Coronary stenting without Coumadin: phase II and III. The bail-out group. // Circulation 1994;90 suppl 1:1-124.

72. Azrin MA, Mitchel JF, Bow LM, et al. Inhibition of smooth muscle cell proliferation in vivo following local delivery of antisense c-myboligonucleotide during angioplasty. // J Am Coll Cardiol 1994;25 suppl:201A.

73. Babbit DG, Perry JM, Forman MB. Intracoronary verapamil for reversal of refractory coronary vasospasm during percutaneous transluminal coronary angioplasty. // J Am Coll Cardiol 1988;12:1377-81.

74. Badak О, Schoenhagen P, Tsunoda T, et al. Atheroma distribution at coronary bifurcations: impact of side branch angulation: an intravascular ultrasound study. J Am Coll Cardiol. 2003;41(Suppl A):2A. Abstract 1005-212.

75. Bailey SR, Ricci D, Kiesz S, et al. Incidence and clinical impact of dissections after PTCA and stent placement: results from the randomized Stent Restenosis Study. // Circulation 1994;90:1-649.

76. Baim DS, Juntz RE, Sharma SK, et al. Acute results of the randomized trial of the Balloon versus Optimal ATherectomy Trial (BOAT). // Circulation 1995;91:1966-74.

77. Baim DS, Kent KM, King SB III, et al for the NACI investigators. Evaluating new devices: Acute (in hospital) results from the New Approaches to Coronary Intervention Registry. // Circulation 1994;89:471-81.

78. Baim DS, Levine MJ, Leon MB, et al. Management of restenosis within the Palmaz-Schatz coronary stent: the U.S. multicenter experience the U.S. Palmaz-Schatz Stent Investigators. // Am J Cardiol 1993;71:364-3 66.

79. Balcon R, Beyar R, Chierchia S, et al. for the Study Group of the Working Group on Coronary Circulation. Recommendations on stent manufacture, implantation and utilization. // Eur Heart J 1997;18:1536-47.

80. Barnathan ES, Schwartz JS, Taylor L, et al. Aspirin and dipyridamole in the prevention of acute coronary thrombosis complicating coronary angioplasty. // Circulation 1987;76:125-34.

81. Bates ER, McGillem MJ, Mickelson JK, et al. A monoclonal antibody against the platelet glycoprotein Ilb/IIIa receptor complex prevents platelet aggregation and thrombosis in a canine model of coronary angioplasty. // Circulation 1991;84:2463-9.

82. Baumbach A, Bittl JA, Fleck E, et al and the coinvestigators for the US and European Percutaneous Excimer Laser Coronary Angioplasty (PELCA) Registries. // J Am Coll Cardiol 1994;23:1305-13.

83. Bauters C, Banos JL, Van Belle E, et al. Six-month angiographic outcome after successful repeat percutaneous intervention for in-stent restenosis. // Circulation 1998;97:318-321.

84. Bauters C, Hubert E, Prat A, et al. Predictors of restenosis after coronary stent implantation. // J Am Coll Cardiol 1998;31:1291-8.

85. Bejarano J, Bermudez E, Diaz P, et al. In-stent restenosis. Acute and long-term outcomes after excimer laser coronary angioplasty. // Arq Bras Cardiol 1999;73(2): 149-56.

86. Belli G, Whitlow PL, Gross L, et al. Intracoronary stenting without oral anticoagulation: the Cleveland Clinic Registry. // Circulation 1995;92 suppl 1:1-796.

87. Belli G, Whitlow PL. Should we spark interest in rotational atherectomy for in-stent restenosis? // Cathet Cardiovasc Diagn 1997;40:150-51.

88. Bergelson BA, Fishman RF, Tommaso CL, et al. Acute and long-term outcome of failed percutaneous transluminal coronary angioplasty treated by directional coronary atherectomy. // Am J Cardiol 1994;73:1224-6.

89. Berger PB, Bell MR, Grill DE, et al. Frequency of adverse clinical events in the 12 months following successful intracoronary stent placement in patients treated with aspirin and ticlopidine (without warfarin). // Am J Cardiol 1998;81:713-718.

90. Berrocal DH, Gonzalez GE, Morales C, et al. Local delivery of irinotecan with drug-eluting stents inhibits neointimal proliferation in hypercholesterolemic rabbits. // J Am Coll Cardiol. 2003;41(Suppl A):16A.

91. Bier JD, Cannistra AJ, Mukherjee S, et al. Histopathologic findings following directional coronary atherectomy performed for failed balloon angioplasty. // Circulation 1994;90:1-63.

92. Black AJ, et al. Tear or dissection after coronary angioplasty. Morphologic correlates of an ischemic complication. // Circulation 1989;79:1035-1042.

93. Bohan M, Yue N, Nath R. On the need for massive additional shielding of a catheterization laboratory for the implementation of high dose rate 192 Ir intravascular brachytherapy. // Cardiovasc Radiat Med 2000;2:39-41.

94. Boland JL, Corbeij HAM, Seabra Gomes R, et al. Multicentre open evaluation of the phosphorylcholine-coated biodivYsio stent in native de novo coronary lesions: the SOPHOS study. // Eur Heart J 1999;20 Suppl:273.

95. Borken AM, Failing RL, Piehler JM, et al. Risk analysis of operative intervention for failed coronary angioplasty. // Ann Thorac Surg 1992;54:884-91.

96. Bossi I, Klersy C, Cortina R, et al. In-stent restenosis patterns predict subsequent target vessel revascularization. // Am J Cardiol 1998;82:74S-75S.

97. Bottner RK, Hardigan KR. High-speed rotational ablation for in-stent restenosis. // Cathet Cardiovasc Diagn 1997;40:144-149.

98. Bowerman RE, Pinkerton CA, Kirk B, Waller BF. Disruption of a coronary stent during atherectomy for restenosis. // Cathet Cardiovasc Diagn 1991;24:248-251.

99. Breaker RR. DNAzymes. // Nature Biotechnol 1997; 15:427-31.

100. Bredee JJ, Bavinck JH, Berreklouw E, et al. Acute myocardial ischemia and cardiogenic shock after percutaneous transluminal coronary angioplasty: risk factors for and results of emergency coronary bypass: // Eur Heart J 1989;10(suppl H): 104-11.

101. Bredlau CE, Roubin GS, Leimgruber PP, et al. In-hospital morbidity and mortality in patients undergoing elective coronary angioplasty. // Circulation 1985;72:1044-52.

102. Brieger D, Topol E. Local drug delivery systems and prevention of restenosis. // Cardiovasc Res 1997;35:405-13.

103. Buchbinder M, Goldberg SL, Fortuna R, et al. Rotational atherectomy for intra-stent restenosis: initial experience. // Circulation 1996;94:I621.

104. Buffet P, Danchin N, Villemot JR, et al. Early and long-term outcome after emergency coronary artery bypass surgery after failed coronary angioplasty. // Circulation 1991;84 suppl 111:111-254-9.

105. Buffet P, Villemot JP, Danchin N, et al. Emergency coronary surgery after transluminal angioplasty. Immediate results and long-term outcome of 100 operations. //Arch Mai Coeurvaiss 1992;85:17-23.

106. Bult H. Restenosis: a challenge for pharmacology. // Trends Pharmacol Sci 2000;21:274-9.

107. Caes FL, van Nooten GJ. Use of internal mammary artery for emergency grafting after failed coronary angioplasty. // Ann Thorac Surg 1994;57:1295-9.

108. Campbell С A, Rezkall S, Kloner RA, Turi ZG. The autoperfusion balloon angioplasty catheter limits myocardial ischemia and necrosis during prolonged balloon inflations. // J Am Coll Cardiol 1989;14:1045-50.

109. Can MK. The use of the guiding catheter in coronary angioplasty: The technique of manipulating catheters to obtain the necessary power to cross tight coronary stenoses. // Cathet Cardiovasc Diagn 1986;12:189-97.

110. Cannon AD, Roubin GS. The Gianturco-Roubin stent. // In Topol EJ, editor. Textbook of interventional cardiology. 2nd ed. Philadelphia: W.B.Saunders 1994;712-26.

111. Cannon RO, Watson RM, Rosing DR et al. Angina caused by reduced vasodilator reserve of tile small coronary arteries. // J Am Coll Cardiol 1983;6:1359-73.

112. Cantor WJ, Peterson ED, Popma JJ, et al. Provisional stenting strategies: systematic overview and implications for clinical decision making. // J Am Coll Cardiol 2001;36:1142-51.

113. Cappalletti A, et al. Short and long-term evolution of unstented nonocclusive coronary dissection after coronary angioplasty. // J Am Coll Cardiol 1999;34,5:1484-8.

114. Carey JA, Davies SW, Balcon R, et al. Emergency surgical revascularization for coronary angioplasty complications. // Br Heart J 1994;72:428-35.

115. Carter AJ, Bailey L, Devries J, Hubbard B. The effects of uncontrolled hyperglycemia on thrombosis and formation of neointima after coronary stent placement in a novel diabetic porcine model of restenosis. // Coron Artery Dis 2000;11:473-9.

116. Carter AJ, Laird JR, Farb A, et al. Morphological characteristics of lesion formation and time course of smooth muscle cell proliferation in a porcine proliferative restenosis model. // J Am Coll Cardiol 1994;139:1398-405.

117. Carter AJ, Welch L, Gibson L, et al. Stents coated with the lipophilic compound A24 (ABT-578) profoundly inhibit neointimal formation in the porcine coronary model. J Am Coll Cardiol. 2003;41(Suppl A):6A.

118. Casserly IP, et al. Usefulness of abciximab for treatment of early coronary artery stent thrombosis. // Am J Cardiol 1998;82(8):981-5.

119. Castagna MT, Mintz GS, Kotani JI, et at. Fixing chronic stent underexpansion is associated with a low rate of recurrence: an intravascular ultrasound analysis. J Am Coll Cardiol. 2003;41(Suppl A):8A. Abstract 1007175.

120. Castagna MT, Mintz GS, Weissman N, et al. "Black hole": echolucent restenotic tissue after brachytherapy. // Circulation 2001;5:778.

121. Cates C, Knopf W, Lembo N, Ryan J. The 80-mm balloon for acute spiral dissections: long-term follow-up. // Circulation 1994;90:1-435.

122. Cattalaens N, Gerckens U, Mueller R, et al. Directional atherectomy for treatment of stent restenosis. Feasibility and long-term follow up in 28 patients. //Am J Cardiol 1998; Suppl 31:TCT 195,A: 1061-60.

123. Caussin C, Alibelli M-J, Elbaz M, et al. Titanium nitride-oxide coated stent: six-month angiographic and intravascular ultrasound follow-up. J Am Coll Cardiol. 2003;41 (Suppl A):7A.

124. Cecena FA. Stenting the stent: alternative strategy for treating in-stent restenosis. // Cathet Cardiovasc Diagn 1996;39:377-382.

125. Chan CNS, Tan ATH, Kah TH, et al. Intracoronary stenting in the treatment of acute or threatened closure in angiographically small coronary arteries <3.0 mm) complicating percutaneous transluminal coronary angioplasty. // Am J Cardiol 1995;75:23-5.

126. Chester MR, Chen L, Kaski J. The natural history of unheralded complex coronary plaques. // J Am Coll Cardiol 1996;28:604-608.

127. Chevalier B, et al. Current indications and results of stent retrieval techniques. // J Am Coll Cardiol 2000;35(2):64A: 1008-176.

128. Chevalier B, Royer T, Glatt B, et al. Preliminary experience of coronary stenting with the Micro Stent. // Circulation 1995;92:suppl 1:1-409.

129. Chevalier B, Royer T, Guyon P, Glatt B. Treatment of Instent Restenosis: Short and Midterm Results of a Pilot Randomized Study Between Balloon and Cutting Balloon. // J Am Coll Cardiol 1999;Suppl A: 1129-51.

130. Cho L. Striking reduction of mortality and target vessel revascularization with stent-abciximab in diabetic women. // J Am Coll Cardiol 2000;35:2:1086-88.

131. Chow WH, Chan TF. Pullback atherectomy for the treatment of intrastent restenosis. // Cathet Cardiovasc Diagn 1997;40:94-95.

132. Christensen CW, Lassar ТА, Daley LC, et al. Regional myocardial blood flow with a reperfusion catheter and an autoperfusion catheter during total coronary occlusion. // Am Heart J 1990; 119:242-8.

133. Cohen DJ, Bakhai A, Shi C, et al. Cost-effectiveness of sirolimus drug-eluting stents for the treatment of complex coronary stenoses: results from the randomized SIRIUS trial. J Am Coll Cardiol. 2003;41(Suppl A):32A.

134. Colombo A, Hall P, Nakamura S, et al. Intracoronary stenting without anticoagulation accomplished with intravascular ultrasound guidance. // Circulation 1995;91:1676-88.

135. Colombo A, Louvard Y, Raghu C, et al. Sirolimus-eluting stents in bifurcation lesions: six-month angiographic results according to the implantation technique. J Am Coll Cardiol. 2003;41(Suppl A):53A.

136. Colombo A, Maiello L, Nakamura S, et al. Preliminary experience of coronary stenting with the Micro Stent. // J Am Coll Cardiol 1995;(suppl):239A.

137. Colombo A, Tobis J. Techniques in Coronary Artery Stenting. Martin Dunitz Ltd. 2000;422.

138. Condalo JA, Waksman R, Gurdiel O, et al. Long-term angiographic and clinical outcome after percutaneous transluminal coronary angioplasty and intracoronary radiation therapy in humans. // Circulation 1997;96:727-32.

139. Costa MA, Moses JW, Leon MB, et al. Sirolimus-eluting stent for the treatment of bypass graft disease: the initial US experience. J Am Coll Cardiol. 2003;41(Suppl A):13A.

140. Costa MA, Sabate M, van der Giessen WJ, et al. Late coronary occlusion after intracoronary brachytherapy. // Circulation 1999;100:789-92.

141. Costa MA, Sousa JEM, Abizaid AA, et al. Three-dimensional intravascular ultrasound assessment after the implantation of estrogen-eluting PC-coated stents in human coronary arteries. J Am Coll Cardiol. 2003;41(Suppl A):5A.

142. Cowley MG, Dorros G, Kelsey SF, et al. Acute coronary events associated with percutaneous transluminal coronary angioplasty. // Am J Cardiol 1984;53:12-6C.

143. Cowley MG, Dorros G, Kelsey SF, et al. Emergency coronary bypass surgery after coronary angioplasty: the National Heart, Lung, and Blood Institute's Percutaneous transluminal coronary angioplasty registry experience. // Am J Cardiol 1984;53:22C-6C.

144. Craver JM, Weintraub WS, Jones EL, et al. Emergency coronary artery bypass surgery for failed percutaneous coronary angioplasty A 10-year experience. // Ann Surg 1992;215:425-33.

145. Cripps TR, Morgan JM, and Rickards AF. Outcome of extensive coronary artery dissection during coronary angioplasty. // Br Heart J 1991;66:3-6.

146. Danchin N, Daclin V, Juilliere Y, et al. Changes in patient treatment after abrupt closure complicating percutaneous transluminal coronary angioplasty: a historic perspective. // Am Heart J 1995; 130:1158-63.

147. Dangas G, Mehran R, Lansky AJ, et al. Acute and long-term results of treatment of diffuse in-stent restenosis in aortocoronary saphenous vein grafts. // Am J Cardiol 2000;86:777-9.

148. Dangas G, Mehran R, Wallenstein S, et al. Correlation of angiographic morphology and clinical presentation in unstable angina. // J Am Coll Cardiol 1997;29:519-525.

149. Daniyarov BS, Batyraliev ТА, Samko AN, et al. Excimer laser angioplasty in patients with acute coronary syndrome. // 49th Annual World Assembly of American College of Angiology 2002;59.

150. Dauerman HL, Baim DS, Cutlip DE, et al. Mechanical debulking versus balloon angioplasty for the treatment of diffuse in-stent restenosis. // Am J Cardiol 1998;82:277-284.

151. Dean LS, Anderson JC, Garrahy PJ, et al. Do standard heparin doses adequately protect patients during coronary angioplasty. // Circulation 1989;80 suppl 1:11-373.

152. Debbas N, Stauffer JC, Eeckhout E, et al. Stenting within a stent: treatment for repeat in-stent restenosis in a venous graft. // Am Heart J 1997; 133:460463.

153. Deckelbaum LI, Natarajan MK, Bittle JA, et al. Effect of intracoronary saline infusion on dissection during excimer laser coronary angioplasty: a randomized trial. // J Am Coll Cardiol 1995;26:1264-1269.

154. Den Heijer P, Foley DP, Hillege H, et al. The "Ermenonville" classification of observations at coronary angioscopy. Evaluation of intra- and interobserver agreement. // Eur Heart J 1994; 15:815-822.

155. Detre KM, Holmes DR Jr, Holubkov R, et al. coinvestigators of the National Heart, Lung, and Blood Institute's Percutaneous Transluminal Coronary

156. Angioplasty Registry. Incidence and consequences of periprocedural occlusion: the 1985-1986 National Heart, Lung and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry. // J Am Coll Cardiol 1990;82:739-748.

157. Detre KM, Holubkov R, Kelsey S, et al. Percutaneous transluminal coronary angioplasty in 1985-1986 and 1978-1981.//N Engl J Med 1988;318:265-70.

158. DeYoung MB, Dichek DA. Gene therapy for restenosis: Are we ready? // CircRes 1998;82:306-13.

159. Di Mario C, Marsico F, Adamian M, et al. New recipes for in-stent restenosis: cut, grate, roast, or sandwich the neointima? // Heart 2000;84:471-5.

160. Domanski MJ, Topol EJ. Cardiogenic shock: current understandings and future research directions. // Am J Cardiol 1994;74:724-6.

161. Dotter CT, Judkins MP. Transluminal treatment of arteriosclerotic obstruction: Description of a new technique and preliminary report of its application. // Circulation 1964;30:654.

162. Dotter CT, Rosch J, Judkins MP. Transluminal dilatation of arteriosclerotic stenosis. // Surg Gynecol Obstet 1968; 127:794.

163. Dougherty KG, Marsh КС, Edelman SK, et al. Relationship between procedural activated clotting time and in-hospital post PTCA outcome. // Circulation 1990;83 suppl 111:111-189.

164. Edelman ER, Rogers C. Hoop dreams. Stent without restenosis. // Circulation 1996;94:1199-1202.

165. Eeckhout E, Wijns W, Meier B, Goy JJ on behalf of the members of the Working Group on Coronary Circulation of the European Society of Cardiology. Indications for coronary stent placement: the European view. // Eur Heart J 1999;20:1014-9.

166. Elezi S, Kastrati A, Neumann FJ, et al. Vessel size and long-term outcome after coronary stent placement. // Circulation 1998;98:1875-80.

167. Elezi S, Kastrati A. Stenting for restenosis of stented lesions: acute and 6 months clinical and angiographic folloow-up. // Circulation 1997;96(suppl I):I 480.

168. Elliott JM, Berdan LG, Holmes DR. One-year follow-up in the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT I). // Circulation 1995;91:2158-66.

169. Ellis SB, Cannon AD, Roubin GS, et al. Coronary stenting. // In Topol EJ, editor. Textbook of interventional cardiology. 2nd ed. Philadelphia: W.B.Saunders 1994;702-741.

170. Ellis SG, Cowley MJ, Whitlow PL, et al. for the multivessel angioplasty prognosis study (MAPS) group. // J Am Coll Cardiol 1995;25:1137-42.

171. Ellis SG, DeCesare NB, Pinkerton CA, et al. Relation of stenosis morphology and clinical presentation to the procedural results of directional coronary atherectomy. // Circulation 1991;84:644-53.

172. Ellis SG, et al. Increased coronary perforation in the new device era. Incidence, classification, management and outcome. // Circulation 1994;90:2725-30.

173. Ellis SG, Roubin GS, King SB III, et al. Angiographic and clinical predictors of acute closure after native vessel coronary angioplasty. // Circulation 1988;77:372-9.

174. Ellis SG, Roubin GS, King SB III, et al. Importance of stenosis morphology in the estimation of restenosis risk after elective percutaneous transluminal coronary angioplasty. // Am J Cardiol 1989;63:30-34.

175. Ellis SG, Roubin GS, King SB III, et al. In-hospital cardiac mortality after acute closure after coronary angioplasty: analysis of risk factors from 8,207 procedures. // J Am Coll Cardiol 1988; 11:211 -6.

176. Ellis SG, Tcheng JE, Navetta FI, et al. Safety and antiplatelet effect of murine monoclonal antibody 7E3 Fab directed against platelet glycoprotein Ilb/IIIa in patients undergoing elective coronary angioplasty. // Coron Artery Dis 1993;4:167-75.

177. Ellis SG, Topol EJ. Results of percutaneous transluminal coronary angioplasty of high-risk angulated stenoses. // Am J Cardiol 1990;66:932-7.

178. Ellis SG, Vandormael MG, Cowley MJ, et al. Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease. Implications for patient selection. // Circulation 1990;82:1193.

179. Eltchaninoff H, Koning R, Tron C, et al. Balloon angioplasty for the treatment of coronary in-stent restenosis: immediate results and 6-months angiographic recurrent restenosis rate. // J Am Coll Cardiol 1998;32:980-4.

180. Emanuelsson H, Serruys PW, Belardi J, et al. Clinical experience with heparin-coated stents: the Benestent II pilot phase I. // J Am Coll Cardiol 1995;(suppl):181A.

181. Emanuelsson H, Serruys PW, van Der Giessen WJ, et al. Clinical and angiographic results with the Multi-Link Coronary Stent System: the West European Stent Trial (WEST). // J Invasive Cardiol 1997; 10 Suppl B:12B-19B.

182. Erbel GGR, Haude M, Kearney P, et al. Continuous coronary perfusion balloon catheters in coronary dissections after percutaneous transluminal coronary angioplasty. // Eur Heart J 1994;15:908-14.

183. Erbel R, Rupprecht HJ, Busch U, et al. Continuous coronary perfusion and prolonged balloon inflation during stenosis dilatation. // Z Kardiol 1987;76:49-52.

184. Escarmant P, Zimmermann S, Amar A, et al. The treatment of 783 keloid scars by iridium 192 interstitial irradiation after surgical excision. // Int J Radiat Oncol Biol Phys 1993;26:245-51.

185. Falcone RA, Werns SW, Muller DWM, et al. The c7E3 platelet antibody inhibits coronary vasoconstriction after coronary angioplasty (PTCA). // Circulation 1994;90:1-258.

186. Farb A, Sangiorgi G, Carter AJ, et al. Pathology of acute and chronic coronary stenting in humans. // Circulation 1999;99: 44-52.

187. Farb A, Virmani R, Atkinson JB, Kolodgie FD. Plaque morphology and pathologic changes in arteries from patients dying after coronary balloon angioplasty. // J Am Coll Cardiol 1990;16:1421-9.

188. Faxon DP, Weber VJ, Haudenschild C, et al. Acute effects of transluminal angioplasty in three experimental models of atherosclerosis. // Arteriosclerosis 1982;2:125-33.

189. Faxon DP, Williams DO, Yeh W, et al. Improved in-hospital outcome with expanded use of coronary stents: results from the NHLBI dynamic registry. // J Am Coll Cardiol 1999;33 Suppl A:91A.

190. Feld S, Ganim M, Carell ES, et al. Comparison of angioscopy, intravascular ultrasound imaging and quantitative coronary angiography in predicting clinical outcome after coronary intervention in high risk patients. // J Am Coll Cardiol 1996;28:97-105.

191. Ferguson JJ III. Conventional antithrombotic approaches. // Am Heart J 1995;130:651-7.

192. Ferguson JJ, Dear WE, Leatherman LL, et al. A multicenter trial of laser balloon angioplasty for abrupt closure following PTCA. // J Am Coll Cardiol 1990;15(suppl A):25A.

193. Fischell RA, Derby G, Tse TM, Stadius ML. Coronary artery vasoconstriction routinely occurs after percutaneous transluminal coronary angioplasty. A quantitative arteriographic analysis. // Circulation 1988;78:1323-34.

194. Fischman DL, Leon MB, Baim DS, et al. A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronaryartery disease: stent restenosis study investigators. // N Engl J Med 1994;331:496-501.

195. Fischman DL, Savage MP, Leon MB, et al. Effect of intracoronary stenting on intimal dissection after balloon angioplasty: results of quantitative and qualitative coronary analysis. // J Am Coll Cardiol 1991;18:1445-51.

196. Fitzgerald PJ, Oshima A, Hayase M, et al. Final results of the Can Routine Ultrasound Influence Stent Expansion (CRUISE) study. // Circulation 2000;201:523-30.

197. Fleser A, et al. The current status of stenting: pathobiology trends. // Cardiovasc Med 1997;7:24-28.

198. Foley D, Pieper M, Wijns W, et al. The influence of stent length on clinical and angiographic outcome in patients undergoing elective stenting for native coronary artery lesions: final results of the Magic 5L Study. // Eur Heart J 2001;22:1585-93.

199. Foley JB, Sridhar K, Dawdy J, et al. Pros and cons of perfusion balloons in failed angioplasty. // Cather Cardiovasc Diagn 1994;31:264-9.

200. Fram DB, McKay RG. "Hot" balloon angioplasty: radiofrequency, Neodynmium: YAG, and microwave. // In Topol EJ, editor. Textbook of interventional cardiology. 2nd ed. Philadelphia: W.B.Saunders 1994;819-39.

201. Frimerman A, Keren G, Rosenschein U, et al. Clinical parameters and functional tests are not predictive for in-stent restenosis. // Int J Cardiovasc Interv 2003;5:151-155.

202. Gallo R, Padurean A, Jayaraman T, et al. Inhibition of intimal thickening after balloon angioplasty in porcine coronary arteries by targeting regulators of the cell cycle. // Circulation 1999;99:2164-70.

203. Garratt KN, White CJ, Buchbinder M, et al on behalf of the American Wiktor Stent Investigators. Wiktor stent placement for unsuccessful coronary angioplasty. // Circulation 1994;90 suppl 1:1-279.

204. Gasperetti CM, Gonias SL, Gimple LW, Powers ER. Platelet activation during coronary angioplasty in humans. // Circulation 1993;88:2728-34.

205. Gibbs JSR, Sigwart U, Buller NP. Temporary stent as a bail-out device during percutaneous transluminal coronary angioplasty: preliminary clinical experience. // Br Heart J 1994;71:372-7.

206. Giri S, Ito S, Lansky AJ, et al. Clinical and angiographic outcome in the Laser Angioplasty for Restenotic Stents (LARS) multicenter registry. // Cathet Cardiovasc Diagn 2001;52:24-34.

207. Glagov S. Intimal hyperplasia, vascular remodeling, and the restenosis problem. //Circulation 1994;89:2888-2891.

208. Goldberg SL, Berger P, Cohen DJ, et al. Rotational atherectomy or balloon angioplasty in the treatment of intra-stent restenosis: BARASTER multicenter registry. // Cathet Cardiovasc Intervent 2000;51:407-13.

209. Goldberg SL, Colombo A, Nakamura S, et al. Benefit of intracoronary ultrasound in the deployment of Palmaz-Schatz stents. // J Am Coll Cardiol 1994;24:996-1003.

210. Goldberg SL, Loussarian A, De Gregorio J et al. When is intra-stent restenosis longer than the original lesion length? A different perspective on "diffuse" restenosis. // Am J Cardiol 1998;suppl:TCT:57.

211. Goldberg SL, Loussarian A, De Gregorio J, et al. Predictors of diffuse and aggressive intrastent restenosis. // J Am Coll Cardiol 2001;37:1019-25.

212. Goldberg SL, Loussarian A, Ferraro M, et al. Predictors of the occurrence and type of in-stent restenosis. // Circulation 1998;98(17):I-1016.

213. Goldberg SL, Shawl F, Buchbinder M, et al. Rotational Atherectomy for In-Stent Restenosis: The BARASTER Registry. // Circulation 1997;Suppl 1:180.

214. Golding LAR, Loop FL, Hollman JL, et al. Early results of emergency surgery after coronary angioplasty. // Circulation 1986;74 suppl 111:111-26-9.

215. Goods CM, Jain SP, Liu MW, et al. Intravascular ultrasound-guided transluminal extraction atherectomy for restenosis after Gianturco-Roubin coronary stent implantation. // Cathet Cardiovasc Diagn 1996;37:317-319.

216. Gordon PC, Gibson CM, Cohen DJ, et al. Mechanism of restenosis and redilation within coronary stents-quantitative angiographic assessment. // J Am Coll Cardiol 1993;21:1166-1174.

217. Gorge G, Erbel R, Haude M, et al. Continuous coronary perfusion balloon catheters in coronary dissections after percutaneous transluminal coronary angioplasty. Acute clinical results and 6-months follow-up. // Eur Heart J 1994;15:908-14.

218. Goy JJ, Eeckhout E, Stauffer JC, et al. Emergency endoluminal stenting for abrupt vessel closure following coronary angioplasty: a randomizedcomparison of the Wiktor and Palmaz-Schatz stents. // Cathet Cardiovasc Diagn 1995;34:128-32.

219. Gregorini L, et al. Normalization of coronary flow reserve after coronary stenting and betal- and beta2- adrenergic antagonist. // J Am Coll Cardiol (suppl.) 2000;35-2:261A, 1067-55.

220. Gregorini L, Marco J, Fajadet J, et al. Ticlopidine and aspirin pretreatment reduces coagulation and platelet activation during coronary dilation procedures. // Am Coll Cardiol 1997;29:13-20.

221. Grewe PH, Deneke T, Machraoui A, et al. Acute and chronic tissue response to coronary stent implantation: pathologic findings in human specimen. // J Am Coll Cardiol 1999;35:157-63.

222. Grines CL, Browne KF, Marco J, et al. A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. // N Engl J Med 1993;328:673-9.

223. Grines CL, Cox DA, Stone GW, et al., the Stent Primary Angioplasty in Myocardial Infarction Study Group. Coronary angioplasty with or without stent implantation for acute myocardial infarction. // N Engl J Med 1999;341:1949-56.

224. Grube E, Buellesfeld L, Mueller R, et al. First human experience using a new everolimus stent coating: procedural and six-month follow-up results of the FUTURE trial. J Am Coll Cardiol. 2003;41 (Suppl A):6A. Abstract 1006183.

225. Grube E. Drug eluting stents: a new era in the stent technology. // Cardiol Int 2001;2:5-6.

226. Gruberg L, et al. The incidence, management and outcome after coronary artery perforation during coronary percutaneous intervention: A single center experience. // J Am Coll Cardiol 2000;35:1085-76.

227. Gruentzig A, Turina M, Schneider J. Experimental percutaneous dilatation of coronary artery stenosis. // Circulation 1976;54:Suppl:81.

228. Gruentzig AR, Senning A, Siegenthaler WE. Nonoperative dilatation of coronary-artery stenosis. Percutaneous transluminal coronary angioplasty. // N Engl J Med 1979;301:61-8.

229. Guameri E, Schatz RA, Sklar MA, et al. Acute coronary syndromes: is it safe to stent? // Circulation 1995;92suppl 1:1-616.

230. Gulba DC, Daniel WG, Rudiger S, et al. Role of thrombolysis and thrombin in patients with acute coronary occlusion during percutaneous transluminal coronary angioplasty. // J Am Coll Cardiol 1990;16:564-8.

231. Gunn J, Cumberland D. Stent coatings and local drug delivery: state of the art. // Eur Heart J 1999;20:1693-700.

232. Gunn J, Holt CM, Francis SE, et al. The effect of oligonucleotides to c-myb on vascular smooth muscle cell proliferation and neointima formation after porcine coronary angioplasty. // Circ Res 1997;80:520-31.

233. Gurbel PA, Navetta FI, Bates ER, et al. Lesionl directed administration of alteplase with intracoronary heparin in patients with unstable angina and coronary thrombus undergoing angioplasty. // Cathet Cardiovasc Diagn 1996;37:382-91.

234. Haase J, Escaned J, van Swijndregt EM, et al. Experimental validation of geometric and densitometric coronary measurements on the newgeneration Cardiovascular Angiography Analysis System (CAAS II). // Cathet Cardiovasc Diagn 1993;30:104 -14.

235. Haase J, Reifart N, Baier T, et al. Bail-out stenting (Palmaz-Schatz) without anticoagulation. // Circulation 1995:92 suppl 1:1-795.

236. Haft JI, Christou CP, Goldstein JE, Carnes RE. Correlation of atherectomy specimen histology with coronary arteriographic lesion morphologic appearance in patients with unstable angina. //Am Heart J 1995;130:420-424.

237. Hall P, Colombo A, Itoh A, et al. Gianturco-Roubin stent implantation in small vessels without anticoagulation. // Circulation 1995;92 suppl 1:1-795.

238. Hamm CW, Beythein C, Siervert H, et al. First clinical experience with the Strecker-stent for acute coronary occlusion after PTCA. // Circulation 1991 ;84 suppl 11:11-198.

239. Handbook of cardiovascular interventions. Ed. By U.Sigwart, M.Bertrand, P.W.Serruys. // Churchill Livingstone, 1996;949.

240. Hansen D, Auth D, Vracko R, Ritchie J. Mechanical thrombectomy: A comparison of two rotational devices and balloon angioplasty in subacute canine femoral thrombosis. // Am Heart J 1987; 114:1223-31.

241. Hara K, Ikari Y, Tamura T, Yamaguchi T. Transluminal extraction atherectomy for restenosis following Palmaz-Schatz stent implantation. // Am J Cardiol 1997;79:801-802.

242. Hasdai D, et al. Coronary angioplasty and intracoronary thrombolysis are of limited efficacy in resolving early intracoronary stent thrombosis. // J Am Coll Cardiol 1996;28(2):361-7.

243. Hasdai D, Garratt KN, Grill DE, et al. Effect of smoking status on the long-term outcome after successful percutaneous coronary revascularization. // N Engl J Med 1997;336:755-761.

244. Haude M, Erbel R, Straub U, et al. Results of intracoronary stents for management of coronary dissection after balloon angioplasty. // Am J Cardiol 1991;67:691-6.

245. Hayase M. Relation between plaque burden and in-stent restenosis: an intravascular ultrasound study. // Circulation 1998;98(17):I-1.

246. Hayerizadeh BF, Marco J. Diagnosis and Management of Acute Complications of Coronary Interventions. // In European Paris Course on Revascularization, Ed. by J.Marco, G.Biamino, J.Fajadet, M.-C. Morice. Paris, 2001;249-268.

247. Hearne SE, et al. Diagnosing coronary arterial stent thrombosis and arterial closure. // Am J Cardiol 1998;82(5):666-8.

248. Heidland UE, Heintzen MP, Michel CJ, Strauer BE. Risk factors for the development of restenosis following stent implantation of venous bypass grafts. //Heart2001;85:312-7.

249. Helft G, Worthley SG, Fuster V, et al. Atherosclerotic aortic component quantification by noninvasive magnetic resonance imaging: an in vivo study in rabbits. // J Am Coll Cardiol 2001 ;37:1149-1154.

250. Hermans WR, et al. Therapeutic dissection after successful coronary balloon angioplasty: no influence on restenosis or on clinical outcome in 693 patients. // J Am Coll Cardiol 1992;20:767-780.

251. Herrmann HC, Buchbinder M, Clemen MW, et al. Emergent use of balloon-expandable coronary artery stenting for failed percutaneous transluminal coronary angioplasty. // Circulation 1992;86:812-9.

252. Herrmann HC, Malosky SA, Guidera SA, et al. Patient selection reduces thrombotic complications of emergent stenting for failed PTCA. // Cathet Cardiovasc Diagn 1995;34:286-92.

253. Heuser RR, Mehta S, Strumpf RK. ACS RX Flow Support Catheter as a temporary stent for dissection or occlusion during balloon angioplasty: Initial experience. // Cathet Cardiovasc Diagn 1992;27:66-74.

254. Heyndrickx GR on behalf of the Benestent study group. BENESTENT-II pilot study: in-hospital results of phase 1,2,3 and 4. // Circulation 1995;92 suppl 1:1-279.

255. Hinohara T, Rowe MH, Robertson GC, et al. Effect of lesion characteristics on outcome of directional coronary atherectomy. // J Am Coll Cardiol 1991;17:1112-20.

256. Hinohara T, Simpson JB, Phillips HR, Stack RS. Transluminal intracoronary reperfusion catheter: a device to maintain coronary perfusion between failed coronary angioplasty and emergency coronary bypass surgery. // J Am Coll Cardiol 1988;11:977-82.

257. Hochman JS, Buller CE, Sleeper LA, et al. Cardiogenic Shock Complicating Acute Myocardial Infarction Etiologies, Management and Outcome: A

258. Report from the SHOCK Trial Registry. Should we emergently revascularize Occluded Coronaries for cardiogenic shock? // J Am Coll Cardiol 2000;36:(suppl A): 1063-70.

259. Hoffman R, Mintz GS, Dussaillant RG, et al. Patterns and mechanisms of in-stent restenosis: a serial intravascular ultrasound study. // Circulation 1996;94:1247-54.

260. Hoffman R, Mintz GS, Mehran R, et al. Intravascular ultrasound predictors of angiographic restenosis in lesions treated with Palmaz-Schatz stents. J Am Coll Cardiol 1998;31:43-9.

261. Hoffman R, Mintz GS. Coronary in-stent restenosis—predictors, treatment and prevention. Eur Heart J 2000;21:1739-49.

262. Hoffmann R, Mintz GS, Mehran R, et al. Intravascular ultrasound predictors of angiographic restenosis in lesions treated with Palmaz-Schatz stents. // J Am Coll Cardiol 1998;31:43-9.

263. Hoffmann R, Mintz GS, Mehran R, et al. Tissue proliferation within and surrounding Palmaz-Schatz stents is dependent on the aggressiveness of stent implantation technique. // Am J Cardiol 1999;83:1170 4.

264. Hoffmann R, Mintz GS, Popma JJ, et al. Chronic arterial responses to stent implantation: a serial intravascular ultrasound analysis of Palmaz-Schatz stents in native coronary arteries. // J Am Coll Cardiol 1996;28:1134-1139.

265. Hoffmann R, Mintz GS. Coronary in-stent restenosis predictors, treatment and prevention. // Eur Heart J 2000;21:1739-49.

266. Hofma SH, van Beusekom HM, Serruys PW, van der Giessen WJ. Recent developments in coated stents. // Curr Intervent Cardiol Rep 2001;3:28-36.

267. Hogrefe RI. An antisense oligonucleotide primer. // Antisense Nucleic Acid DrugDev 1999;9:351-7.

268. Hoher M, Worhle J, Wohlfrom M, et al. Intracoronary betairradiation with a liquid (188)Re-filled balloon: six-month results from a clinical safety and feasibility study. // Circulation 2000;101:2355-60.

269. Hollman J, Gruentzig AR, Douglas JS, et al. Acute occlusion after percutaneous transluminal coronary angioplasty a new approach. // Circulation 1983;68:725-32.

270. Holmes DR Jr, Fitzgerald P, Goldberg S, et al. The PRESTO (Prevention of Restenosis with Tranilast and its Outcomes) protocol: a double-blind, placebo-controlled trial. // Am Heart J 2000;139:23-31.

271. Holmes DR Jr, Hirshfeld J Jr, Faxon D, et al. ACC Expert Consensus Document on Coronary Artery Stents. J Am Coll Cardiol 1998;32:1471-82.

272. Holmes DR Jr, Simpson JB, Berdan LG, et al. for the CAVEAT I Investigators. Abrupt Closure: the CAVEAT I Experience. // J Am Coll Cardiol 1995;26:1494-1500.

273. Holmes DR, Leon MB, Moses JW, et al. One-year follow-up of the SIRIUS study: a randomized study with the sirolimus-eluting Bx-VELOCITY in the treatment of patients with de-novo native coronary artery lesions. J Am Coll Cardiol. 2003;41(Suppl A):32A.

274. Нопуе J, Mahon DJ, Jain A, et al. Morphological effects of coronary balloon angioplasty in vivo assessed by intravascular ultrasound imaging. // Circulation 1992;85:1012-25.

275. Hosmer DW, Lemeshow S. Applied Logistic Regression. // 2nd ed. New York: Wiley 2000.

276. Hou D, Narciso H, Kamdar K, et al. Reducing neointimal proliferation by a stent-based delivery of nitric oxide in a porcine carotid overstretch injury model. J Am Coll Cardiol. 2003;41(Suppl A):6A.

277. Huber MS, et al. Use of a morphologic classification to predict clinical outcome after dissection from coronary angioplasty. // Am J Cardiol 1991;68:467-471.

278. Ito H, et al. Clinical Implications of the "No Reflow' Phenomenon: A Predictor of Complications and Left Ventricular Remodeling in Reperfused Anterior Wall Myocardial Infarction. // Circulation 1993;223-228.

279. Ito H, et al. Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction. //Circulation 1985;1699-1705.

280. Jackman JD, Zidar JP, Tcheng JE, et al. Outcome after prolonged balloon inflations of >20 minutes for initially unsuccessful percutaneous transluminal coronary angioplasty. // Am J Cardiol 1992;69:1417-21.

281. Jayaraman T, Marks AR. Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line. // J Biol Chem 1993;268:25385-25388.

282. Jenkins RD, Sinclair IN, McCall PE, et al. Thermal sealing of arterial dissections and perforations in atherosclerotic rabbits with laser balloon angioplasty. // Lasers Life Sci 1989;3:13-30.

283. Jenkins RD, Spears JR. Laser balloon angioplasty: a new approach to abrupt coronary occlusion and chronic restenosis. // Circulation 1990;81(suppl IV):IV-101-6.

284. Judkins MP. Selective coronary arteriography: I. A percutaneous transfemoral technique. // Radiology 1967;89:815-24.

285. Jutzy KR. Coronary angioplasty in the United States. // Rev Port Cardiol 1999; 18:Suppl 1:37-46.

286. Kahlon JP, Torey J, Ali A, et al. Intracoronary calcium and coronary artery disease risk factors: an intravascular ultrasound study. J Am Coll Cardiol. 2003;41 (Suppl A): 9A. Abstract 1007-200.

287. Kar S, Honda T, Mcclean D, et al. Elution of everolimus and sirolimus from a biodegradable polymer coated stent inhibits neointimal hyperplasia without inflammation or toxicity. J Am Coll Cardiol. 2003 ;41 (Suppl A):6A.

288. Kasaoka S, Tobis J, Akiyama T, et al. Angiographic and intravascular ultrasound predictors of in-stent restenosis. // J Am Coll Cardiol 1998;32:1630 -5.

289. Kaski JC, Chester MR, Chen L, Katritsis D. Rapid angiographic progression of coronary artery disease in patients with angina pectoris. The role of complex stenosis morphology. // Circulation 1995;92:2058-2065.

290. Kastrati A, Dirschinger J, Schomig A. Genetic risk factors and restenosis after percutaneous coronary interventions. // Herz 2000;25: 34-46.

291. Kastrati A, Elezi S, Dirschinger J, et al. Influence of lesion length on restenosis after coronary stent placement. // Am J Cardiol 1999;83:1617-22.

292. Kastrati A, Koch W, Berger PB, et al. Protective role against restenosis from an interleukin-receptor antagonist gene polymorphism in patients treated with coronary stenting. // J Am Coll Cardiol 2000;36:2168-73.

293. Kastrati A, Koch W, Elezi S et al. Insertion/deletion polymorphism of angiotensin-converting enzyme and restenosis after coronary stent placement. // Circulation 1998;98(17):I-1-1016.

294. Kastrati A, Mehilli J, Dirschinger J, et al. Restenosis after coronary placement of various stent types. // Am J Cardiol 2001;87:34-9.

295. Kastrati A, Schomig A, Elezi S, et al. Interlesion dependence of the risk for restenosis in patients with coronary stent placement in multiple lesions. Circulation 1998;97:396-401.

296. Kastrati A, Schomig A, Elezi S, et al. Predictive factors of restenosis after coronary stent placement. J Am Coll Cardiol 1997;30:1428-36.

297. Kastrati A, Schoming A, Seyfarth M, et al. PIA polymorphism of platelet glycoprotein Ilia and risk of restenosis after coronary stent placement. Circulation 1999;99:1005-10.

298. Kastrati A, Seyfarth M, Koch W et al. PIA polymorphism of the platelet glycoprotein Ilia is associated with higher risk of and restenosis after coronary stent placement. Circulation 1998; 98 (17):l-l to 1-1016.

299. Katsuomi I, et al. Alternation in the Coronary Blood Flow Velocity Pattern in Patients With No Reflow and Reperfused Acute Myocardial Infarction. Circulation 1994; 1269-1275.

300. Kay IP, Wardeh AJ, Kozuma K, et al. Radioactive stents delay but do not prevent in-stent neointimal hyperplasia. Circulation 2001;103:14-7.

301. Keane D, Roubin GS, Marco J, et al. GRACE-Gianturco-Roubin stent acute closure evaluation: substrate, challenges, and design of a randomized trial of bailout management. J Interv Cardiol 1994;7:333-9.

302. Kearney M, Pieczek A, Haley L, et al. Histopathology of in-stent restenosis in patients with peripheral artery disease. Circulation 1997;95:1998-2002.

303. Kendal DG. Rank Correlation Methods. 3rd ed. London: Charles Griffin, 1962.

304. Kent KM, Cowley MG, Kelsey CF, et al. Contributors to the NHLBI PTCA Registry: Long-term follow-up of the NHLBI PTCA-registry. Circulation 1986;74:Suppl. 11:280.

305. Kereiakes D, Linnemeier TJ, Baim DS, et al. Usefulness of stent length in predicting in-stent restenosis (the MULTI-LINK stent trials). Am J Cardiol 2000;86:336-41.

306. Kereiakes DJ, Kleiman NS, Ambrose J, et al. Randomized, double-blind, placebo-controlled dose-ranging study of tirofiban (MK-383) platelet Ilb/IIIa blockade in high risk patients undergoing coronary angioplasty. J Am Coll Cardiol 1996;27:536-42.

307. Kereiakes DJ, Sketch MH, Ohman EM. Perfusion balloon angioplasty in patients with complex lesion morphology. J Invas Cardiol 1995;7:4B-9B.

308. Kern MJ, Aguirre FV, Bach RG, et al. Restoration of normal phasic flow velocity after multiple coronary artery stent placement. Am Heart J 1994;127:204-7.

309. Kern MJ, Eilen SD. Coronary vasospasm complicating PTCA. Am Heart J 1985;109:1098-101.

310. Khachigian LM. Catalytic DNAs as potential therapeutic agents and sequence-specific molecular tools to dissect biologic function. J Clin Invest 2000;106:1189-95.

311. Killen DA, Hamaker WR, Reed WA. Coronary artery bypass following percutaneous transluminal coronary angioplasty. Ann Thorac Surg 1985;40:133-8.

312. Kim HS, Waksman R, Cottin Y, et al. Edge stenosis and geographical miss following intracoronary gamma radiation therapy for instent restenosis. J Am Coll Cardiol 2001;37:1026-30.

313. Kim H-S, Yazdi HA, Dangas G, et al. Local delivery of thirdgeneration antisense drug inhibits neointimal formation after stent implantation in the porcine coronary artery. J Am Coll Cardiol 2001;37:44A.

314. Kim W, Jeong MH, Cha GS, et al. The effect of carvedilol-loaded BiodivYsio stent on neointimal hyperplasia in a porcine coronary stent restenosis model. J Am Coll Cardiol. 2003;41(Suppl A):31A.

315. King SB III, Lembo NJ, Weintraub WS, et al. A randomized trial comparing coronary angioplasty with coronary bypass surgery. N Engl J Med 1994;331:1044-50.

316. King SB III, Williams DO, Chougule P, et al. Endovascular beta-radiation to reduce restenosis after coronary balloon angioplasty: results of the beta energy restenosis trial (BERT). Circulation. 1998; 97: 2025-30.

317. Kini A, Marmur JD, Dangas G, et al. Angiographic patterns of in-stent restenosis and implications on subsequent revascularization. // Cathet Cardiovasc Intervent 2000;49:23-29.

318. Kleiman NS. Description of patients undergoing high risk angioplasty. Analyses of various databases. Eur Heart J 1995;16:30-5.

319. Klepzig H Jr, Kober G, Kaltenbach M. Analysis of 100 emergency aortocoronary bypass operations after percutaneous transluminal coronary angioplasty: which patients are at high risk for large infarctions? Eur Heart J 1991;12:946-51.

320. Klues HG, Reffelmann T, von Dahl J, Hanrath DP. High-speed rotational coronary atherectomy for the treatment of restenosis in coronary stents. J Am Coll Cardiol 1997;29:313A.

321. Klugherz BD, Jones PL, Cui X, et al. Gene delivery from a DNA controlled-release stent in porcine coronary arteries. Nature Biotech 2000; 18:1181-4.

322. Kobayashi Y, De Gregorio J, Kobayashi N, et al. Stented segment length as an independent predictor of restenosis. J Am Coll Cardiol 1999;34:651-9.

323. Komatsu R, Ueda M, Naruko T, et al. Neointimal tissue response at sites of coronary stenting in humans: macroscopic, histological, and immunohistochemical analyses. Circulation 1998;98:224-33.

324. Konstantinos К, Kamat SG, Schafer Al, et al. Shear-induced platelet aggregation in humans is inhibited by infusion of an anti-glycoprotein IIB/IIIA antibody, c7E3-Fab. Circulation 1994;90:1-568.

325. Kornowski R, Hong MK, Fermin ОТ, et al. In-stent restenosis: contributions of inflammatory responses and arterial injury to neointima hyperplasia. J Am Coll Cardiol 1998;31: 224-30.

326. Kornowski R, Hong MK, Tio FO, et al. In-stent restenosis: contributions of inflammatory responses and arterial injury to neointimal hyperplasia. J Am Coll Cardiol 1998;31:224-30.

327. Kornowski R, Mintz GS, Kent KM, et al. Increased restenosis in diabetes mellitus after coronary interventions is due to exaggerated intimal hyperplasia: a serial intravascular ultrasound study. Circulation 1997;95:1366 -9.

328. Kosokabe T, Okumura K, Sone T, et al. Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplasia after coronary stenting. Circulation 2001;103:2048-54.

329. Koster R, Hamm CW, Terres W, et al. Long-term results of laser angioplasty for in stent restenosis. J Am Coll Cardiol. 1998; 31 Suppl A: 1060-84.

330. Koster R, Hamm CW, Terres W, et al. Treatment of in-stent coronary restenosis by excimer laser angioplasty. Am J Cardiol 1997;80:1424 -1428.

331. Koster R, Kahler J, Terres W, et al. Six-month clinical and angiographic outcome after successful excimer laser angioplasty for in-stent restenosis. J Am Coll Cardiol 2000;36:69-74.

332. Koster R, Vieluf D, Kiehn M, et al. Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet 2000; 356:1895— 7.

333. Koster RP, Koschyk DH, Kahler J, et al. Laser angioplasty on in-stent restenosis. Circulation 1996;94(Suppl):I621.

334. Kotani J, Mintz GS, Castagna MT, et al. What are the differences between culprit and nonculprit lesions in patients with acute myocardial infarction? J Am Coll Cardiol. 2003;41(Suppl A):41A. Abstract 1102-179.

335. Kotani J, Mintz GS, Pregowski J, et al. Does a thrombotic lesion detected by coronary angiography always contain a thrombus? An intravascular ultrasound study. J Am Coll Cardiol. 2003;41(Suppl A):9A. Abstract 1007201.

336. Krone RJ, Laskey WK, Johnson C, et al. A simplified lesion classification for predicting success and complications of coronary angioplasty. Am J Cardiol, 2000, 85, p. 1179-84.

337. Krupski WC, Bass A, Kelly AB, et al. Reduction in thrombus formation by placement of endovascular stents at endarterectomy sites in baboon carotid arteries. Circulation 1991 ;84: 1749-57.

338. Kuntz RE, Baim DS. Defining coronary restenosis: newer clinical and angiographic paradigms. Circulation 1993;88:1310-23.

339. Kuntz RE, Baim DS. Prevention of coronary restenosis: the evolving evidence base for radiation therapy. Circulation 2000; 101:2130-33.

340. Kuntz RE, Gibson CM, Nobuyoshi M, et al. Generalized model of restenosis after conventional balloon angioplasty, stenting and directional atherectomy. J Am Coll Cardiol. 1993; 21: 15-25.

341. Kuntz RE, Keaney KM, Sennerchia C, Baim DS. Estimating the late results of coronary intervention from incomplete angiographic follow-up. Circulation 1993;87:815-30.

342. Kuntz RE, Piana R, Pomerantz RM, et al. Changing incidence and management of abrupt closure following coronary intervention in the new device era. Cathet Cardiovasc Diagn 1992;27:183-90.

343. Kuntz RE, Safian RD, Carrozza JP, et al. The importance of acute luminal diameter in determining restenosis after coronary atherectomy or stenting. Circulation 1992;86:1827-35.

344. Kuntz RE. Stent plus radiation: no sure cure for stenosis. JAMA 2001;285:2069.

345. Kwok OH, Chow WH, Lee CH, et al. First-in-human study of angiopeptin-eluting stents: a quantitative coronary angiography and volumetric intravascular ultrasound study. J Am Coll Cardiol. 2003;41(Suppl A):6A.

346. Laham RJ, Carrozza JP, Berger C, et al. Long-term (4- to 6-year) outcome of Palmaz-Schatz stenting: paucity of late clinical stent-related problems. J Am Coll Cardiol. 1996; 28: 820-26.

347. Laird JR, Popma JJ, Knopf WD, et al. Angiographic and procedural outcome after coronary angioplasty in high-risk subsets using a decremental diameter (tapered) balloon catheter. Tapered Balloon Registry Investigators. Am J Cardiol 1996;77:561-8.

348. Lam JY, Chesebro JH, Steele PM, et al. Antithrombotic therapy for deep arterial injury by angioplasty. Efficacy of common platelet inhibition compared with thrombin inhibition in pigs. Circulation 1991;84:814-20.

349. Landau C, Jacobs AK, Currier JW, et al. Long-term clinical follow-up of patients successfully treated with a perfusion balloon catheter for coronary angioplasty-induced dissections or abrupt closure. Am J Cardiol 1994;74:733-5.

350. Landau C, Lange RA, Hillis LD. Percutaneous transluminal coronary angioplasty. N Eng J Med 1994;330:981-93.

351. Lane DM. Dramatic increase in the use of coronary stents. Am J Cardiol 1999;84:1141.

352. Lansky AJ, Roubin GS, O'Shaughnessy CD, et al. Randomized comparison of GR-II stent and Palmaz-Schatz stent for elective treatment of coronary stenosis. Circulation 2000;102:1364-8.

353. Laskey MA, Deutsch E, Barnathan E, Laskey WK. Influence of heparin therapy on percutaneous transluminal coronary angioplasty outcome in unstable angina pectoris. Am J Cardiol 1990;65:1425-9.

354. Lauer B, Schmidt E, Ambrosch H, et al. Optimal Treatment of In-Stent-Restenosis: Excimerlaser-Angioplasty, Rotational Atherectomy or Conventional Angioplasty? J Am Coll Cardiol 1999;Suppl A: 1129-60;

355. Lazar HL, Faxon DP, Paone G, et al. Changing profiles of failed coronary angioplasty patients: impact on surgical results. Ann Thorac Surg 1992;53:269-73.

356. Lazar HL, Haan CK. Determinants of myocardial infarction following emergency coronary artery bypass for failed percutaneous coronary angioplasty. Ann Thorac Surg 1987;44:646-50.

357. Lee SG, Lee CW, Cheong SS, et al. Immediate and long-term outcomes of rotational atherectomy versus balloon angioplasty alone for treatment of diffuse stent restenosis. Am J Cardiol 1988;82:140-143.

358. Lee TC, Hartzler GO, Rutherford BD, McConahay DR. Removal of an occlusive coronary dissection flap by using an atherectomy catheter. Cathet Cardiovasc Diag 1990;20:185-188.

359. Lefevre T, Louvard Y, Morice MC et al. In stent restenosis. Should we stent the stent? A single center prospective study. Circulation 1997; 96(suppl I): 1481.

360. Leitschuh ML, Mills RM Jr, Jacobs AK, et al. Outcome after major dissection during coronary angioplasty using the perfusion balloon catheter. Am J Cardiol 1991;67:1056-60.

361. Lembo NJ, Black AJR, Roubin GS, et al. Effect of pretreatment with aspirin versus aspirin plus dipyridamole on the frequnecy and type of acute complications of percutaneous transluminal coronary angioplasty. Am J Cardiol 1990;65:422-6.

362. Leon MB, Cutlip DE, Fitzpatrick M, et al. Acute results and one-year outcomes of the Stent Antithrbmbotic Regimen Study (STARS) registry. Circulation 1997;96:Suppl 1:594.

363. Leon MB, et al. A Clinical Trial Comparing Three Antithrombotic-Drug Regimens after Coronary-Artery Stenting, N Engl J Med 1998;339:1665-71.

364. Leon MB, Moses JW, Weisz G, et al. The frequency and consequences of angiographic aneurysms after sirolimus-eluting stents: results from SIRIUS. J Am Coll Cardiol. 2003;41(Suppl A):13A.

365. Leon MB, Popma JJ, Yakubov S, et al. The effects of sirolimus-eluting stents on in-stent and peri-stent restenosis: an angiographic subanalysis from the SIRIUS trial. J Am Coll Cardiol. 2003;41(Suppl A):14A.

366. Leon MB, Teirstein PS, Moses JW, et al. Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting. N Engl J Med 2001;344:250-6.

367. Leopold J, Jacobs A. "Treatment of Closure and Threatened Closure" In: Strategic approaches in coronary intervention, 2nd edition, 2000; Lippincott Williams & Wilkins.

368. Levin DC, Fallon JT. Significance of the angiographic morphology of localized coronary stenoses: histopathologic correlations. Circulation 1982;66:316-320.

369. Levy G, de Boisgelin X, Volpiliere R, et al. Intracoronary stenting in direct infarct angioplasty: is it dangerous? Circulation 1995;92 suppl 1:1-139.

370. Li Y, Breaker RR. Deoxyribozymes: new players in the ancient game of biocatalysis. Curr Opin Structural Biol 1999;9:315-23.

371. Liistro F, Colombo A. Late acute thrombosis after paclitaxel eluting stent implantation. Heart 2001;86:262-4.

372. Lincoff AM, Popma JJ, Ellis SG, Topol EJ. Abrupt vessel closure complicating coronary angioplasty: clinical, angiographic and therapeutic profile. J Am Coll Cardiol 1992;19:926-35.

373. Lincoff AM, Topol EJ, Califf RM, et al. Influence of platelet GP Ilb/IIIa receptor inhibition with c7E3 on the sequelae of dissection during percutaneous coronary revascularization. J Am Coll Cardiol 1995;25(suppl):390A.

374. Lincoff AM, Topol EJ, Chapekis AT, et al. Intracoronary stenting compared with conventional therapy for abrupt vessel closure complicating coronary angioplasty: a matched case-control study. J Am Coll Cardiol 1993;21:866-75.

375. Linker DT, Brown BG. Remodeling of human coronary arteries over time in vivo. J Am Coll Cardiol. 2003;41(Suppl A):299A. Abstract 1179-149.

376. Litvack F, Eigler N, Margolis J, et al. Percutaneous excimer laser coronary angioplasty. Am J Cardiol, 1990, 66, p. 1027-32.

377. Litvack F, Grundfest W, Goldenberg T, et al. Percutaneous excimer laser angioplasty of aortocoronary saphenous vein grafts. J Am Coll Cardiol, 1989, 14, p.803-8.

378. Litvack F. Excimer laser coronary angioplasty. In: Topol EJ, editor. Textbook of interventional cardiology, 2nd ed. Philadelphia: W.B.Saunders 1994;840-858.

379. Liu, et al. Coronary Arterial perforation: prediction, diagnosis, management, and prevention In: "Strategic approaches in coronary intervention", 2nd edition. Lippincott Williams & Wilkins 2000;501-514.

380. Lowe HC, Chesterman CN, Khachigian LM. Does thrombus contribute to in-stent restenosis in the porcine coronary stent model? Thromb Haemost 2001;85:1117-8.

381. Lowe HC, Fahmy RG, Kavurma MM, et al. Catalytic oligodeoxynucleotides define a critical regulatory role for early growth response factor-1 in porcine coronary in-stent restenosis. Circ Res 2001;89:670-7.

382. Lowe HC, Oesterle SN, Khachigian LM. Coronary in-stent restenosis: Current status and future strategies. J Am Coll Cardiol 2002;39:183-193.

383. Lyons RT, Zarins CK, Lu CT, et al. Vessel plaque and lumen morphology after transluminal balloon angioplasty: quantitative study in distended human arteries. Arteriosclerosis 1987;7:306-14.

384. Mabin ТА, Holmes DR Jr, Smith HC, et al. Intracoronary thrombus: role in coronary occlusion complicating percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 1985;5:198-202.

385. Mac Neill BD, Lowe HC, Pomeranstev E, et al. In-vivo characterization of plaque morphology by optical coherence tomography predicts coronary artery remodeling. J Am Coll Cardiol. 2003;41(Suppl A):42A. Abstract 1102-183.

386. Macander PJ, Roubin GS, Agrawal SK, et al. Balloon angioplasty for treatment of in-stent restenosis: feasibility, safety, and efficacy. Cathet Cardiovasc Diagn 1994;32:125-131.

387. Macaya C, Serruys PW, Ruygrok PW, et al. Continued benefit of coronary stenting versus balloon angioplasty: One-year clinical follow-up of Benestent trial. 8th complex coronary angioplasty course, Paris, 1997, p.783-91.

388. Macejak DG, Lin H, Webb S, et al. Adenovirus-mediated expression of a ribozyme to c-myb mRNA inhibits smooth muscle cell proliferation and neointima formation in vivo. J Virol 1999;73:7745-51.

389. Mach F. Toward new therapeutic strategies against neointimal formation in restenosis. Atheroscler Thromb Vase Biol 2000;20: 1699-700.

390. Mahdi NA, Pathan AZ, Harrell L, et al. Directional coronary atherectomy for the treatment of Palmaz-Schatz in-stent restenosis. Am J Cardiol 1998;82:1345-51.

391. Maiello L, Colombo A, Gianrossi R, et al. Coronary stenting for treatment of acute or threatened closure following dissection after coronary balloon angioplasty. Am Heart J 1993;125:1570-5.

392. Makkar RR, Eigler NL, Nakamura M, et al. Monoclonal antibody to Ilb-IIIa receptor (m7E3) is highly effective in inhibiting acute stent thrombosis. Circulation 1995;92 suppl 1:1-685.

393. Mancini GB, Simon SB, McGillem MJ, et al. Automated quantitative coronary arteriography: morphologic and physiologic validation in vivo of a rapid digital angiographic method. Circulation 1987;75:452-60.

394. Marquis JR, Schwartz L, Aldridge H, et al. Acute coronary artery occlusion during percutaneous transluminal coronary angioplasty treated by redilation of the occluded segment. J Am Coll Cardiol 1984;4:1268-71.

395. McGarry TF Jr, Gottlieb RS, Morganroth J, et al. The relationship of anticoagulation level and complications after successful percutaneous transluminal coronary angioplasty. Am Heart J 1992;123:1445-51.

396. McKeever LS, Marek JC, Kerwin PM, et al. Bail-out directional atherectomy for abrupt coronary artery occlusion following conventional angioplasty. Cathet Cardiovasc Diagn 1993;(suppl l):31-6.

397. McNamara CA, Sarembock IJ, Gimple LW, et al. Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor. J Clin Invest 1993;91:94-8.

398. Meany ТВ, Leon MB, Kramer BL, et al. Transluminal extraction catheter for the treatment of diseased saphenous vein grafts: a multicenter experience. Cathet Cardiovasc Diagn 1995;34:112-20.

399. Meckel CR, Kjelsberg MA, Ahmed WH, et al on behalf of the Hirulog Angioplasty Study Investigators. Bailout stenting for abrupt vessel closure during coronary angioplasty. Circulation 1995;92 suppl 1:1-688.

400. Mehan VK, Kaufmann U, Urban P, et al. Stenting with the half (disarticulated) Palmaz-Schatz stent. Cathet Cardiovasc Diagn 1995;34:122-7.

401. Mehran R, Abizaid AS, Mintz GS, et al. Patterns of in-stent restenosis: classification and impact on subsequent target lesion revascularization. J Am Coll Cardiol. 1998;31:Suppl A: 1060-85.

402. Mehran R, Ambrose JA, Bongu RM, et al. Angioplasty of complex lesions in ischemic rest angina: results of the Thrombolysis and Angioplasty in Unstable Angina (TAUSA) trial. J Am Coll Cardiol 1995;26:961-6.

403. Mehran R, Dangas G, Abizaid A, et al. Angiographic patterns of in-stent restenosis: classification and implications for long-term outcome. Circulation 1999;100:1872-8.

404. Mehran R, Dangas G, Abizaid A, et al. Treatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: short- and long-term results. Am Heart J 2001; 141:610-4.

405. Mehran R, Dangas G, Mintz GS, et al. Excimer laser vs. rotational atherectomy for the treatment of diffuse in-stent restenosis: Acute and long-term results. J Am Coll Cardiol 1999; Suppl A: 1129-91.

406. Mehran R, Ito S, Abizaid A, et al. Does lesion length affect late outcome of patients with in-stent restenosis? Results of the multicenter Laser Angioplasty for Stent Restenosis (LARS) registry. J Am Coll Cardiol 1998;31:142A.

407. Mehran R, Mintz GS, Pichard AD, et al. Morphologic and procedural predictors of diffuse in-stent restenosis. J Am Coll Cardiol 1997;29:76A.

408. Mehran R, Mintz GS, Popma J, et al. Mechanisms and results of balloon angioplasty for the treatment of in-stent restenosis. Am J Cardiol 1996;78:618-22.

409. Mehran R, Mintz GS, Popma JJ, et al. Mechanisms of lumen enlargement during atheroablation of in-stent restenosis: a volumetric ultrasound analysis. J Am Coll Cardiol 1997;29:497A.

410. Mehran R, Mintz GS, Popma JJ, et al. Treatment of in-stent restenosis: a intravascular ultrasound study of results in 159 stented lesions. J Am Coll Cardiol 1997;29:77A.

411. Mehran R, Mintz GS, Satler LF, et al. Treatment of in-stent restenosis with excimer laser coronary angioplasty: mechanisms and results compared with PTCA alone. Circulation 1997;96:2183-2189.

412. Meier B. Surgical standby for PTCA. In Topol EJ, editor. Textbook of interventional cardiology, 2nd ed. Philadelphia: W.B.Saunders 1994;565-75.

413. Meyer BJ, Fernandez-Ortiz A, Mailhac A, et al. Local delivery of r-hirudin by a double-balloon perfusion catheter prevents mural thrombosis and minimizes platelet deposition after angioplasty. Circulation 1994;90:2474-80.

414. Meyer T, Schmidt T, Buchwald A, Wiegand V. Stent wire cutting during coronary directional atherectomy. Clin Cardiol 1993;16:450-452.

415. Miller GJ, Bauer KA, Cooper JA, Rosenberg RD. Activation of the coagulant pathway in cigarette smokers. Thrombosis Haemostasis 1998;79:549-553.

416. Mills NL, Bringaze WL. Preparation of the internal mammary artery graft. J Thorac Cardiovasc Surg 1989;98:73-9.

417. Mintz GS, Hoffmann R, Mehran R, et al. In- stent restenosis: The Washington Hospital Center Experience. Am J Cardiol 1998;81:(suppl 7A)7E-13E.

418. Mintz GS, Mehran R, Waksman R, et al. Treatment of in-stent restenosis. Semin Interv Cardiol 1998;3:117-21.

419. Mintz GS, Popma JJ, Pichard AD, et al. Arterial remodeling after coronary angioplasty: a serial intravascular ultrasound study. Circulation 1996;94:35-43.

420. Mittal S, Weiss DL, Hirshfeld JWJ, et al. Comparison of outcome after stenting for de novo versus restenotic narrowings in native coronary arteries. Am J Cardiol 1997;80:711-5.

421. Moreno PR, Bernardi VH, Lopez-Cuellar J, et al. Macrophage infiltration predicts restenosis after coronary intervention in patients with unstable angina. Circulation 1996;94:3098 -102.

422. Moreno PR, Fallon JT, Murcia AM, et al. Tissue characteristics of restenosis after percutaneous transluminal coronary angioplasty in diabetic patients. J Am Coll Cardiol 1999;34:1045-9.

423. Moreno PR, Garcia E, Soriano J, et al. Long-term outcome of patients with proximal left anterior descending coronary artery in-stent restenosis treated with rotational atherectomy. Cathet Cardiovasc Intervent 2001;52:435-42.

424. Moreno PR, Palacios IF, Leon MN, et al. Histopathologic comparison of human coronary in-stent and postballoon angioplasty restenotic tissue. Am J Cardiol 1999;84:462-6.

425. Morice MC, Breton C, Bunouf P, et al. Coronary stenting without anticoagulant, without intravascular ultrasound. Results of the French Registry. Circulation 1995:92(suppl I):I-796.

426. Morice MC, Duman P, Voudris V, et al. The MUST Trial. In-hospital and clinical events at six months. Final results. J Am Coll Cardiol 1997; 29 (suppl A): 93A.

427. Morice M-C, Serruys PW, Sousa JE, et al, for the RAVEL Study Group. A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med. 2002;346:1773-1780.

428. Moris C, Alfonso F, Lambert JL, et al. Stenting for coronary dissection after balloon dilation of in-stent restenosis: stenting a previously stented site. Am Heart J 1996;131:834-836.

429. Moses JW, Leon MB, Popma JJ, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349:1315-23.

430. Moussa I, Colombo A. Coronary stenting: "Current state of the art". Rev Port Cardiol 1999;18:Suppl 1:75-84.

431. Moussa I, et al. Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation. Circulation 1999;99(18):2364-6.

432. Moussa I, et al. Subacute stent thrombosis in the era of intravascular ultrasound-guided coronary stenting without anticoagulation: frequency, predictors and clinical outcome. J Am Coll Cardiol 1997;29(1):6-12.

433. Moussa I, Moses J, Di Mario C, et al. Stenting after Optimal Lesion Debulking (SOLD) registry. Circulation 1998;98:1604-9.

434. Mudra H, Regar E, Klauss V, et al. Serial follow-up after optimized ultrasound guided deployment of Palmaz-Schatz stents. Circulation 1997;95:363-70.

435. Muhlestein JB, Gomez MA, Karagonunis LA, Anderson JL. "Rescue RePro": acute utilization of abciximab for the dissolution of coronary thrombus developing as a complication of coronary angioplasty . Circulation 1995:92 suppl 1:1-607.

436. Muller DW, Golomb G, Gordon D, Levy RJ. Site-specific dexamethasone delivery for the prevention of neointimal thickening after vascular stent placement. Coron Artery Dis 1994;5:435-42.

437. Muller DWM, Ellis SG, Topol EJ. Experimental models of coronary artery restenosis. J Am Coll Cardiol 1992;19:418-32.

438. Muller, et al. A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary artery stents. Circulation 2000; 101:590-593.

439. Munro TR. The relative radiosensitivity of the nucleus and cytoplasm of Chinese hamster fibroblasts. Radiat Res 1970;42:451-70.

440. Muotri AR, Pereira LV, Vasques LR, Menck CFM. Ribozymes and the anti-gene therapy: how a catalytic RNA can be used to inhibit gene function. Gene 1999;237:303-10.

441. Muranaka Y, Yamasaki Y, Nozawa Y, et al. TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries. J Pharmacol Exp Ther 1998;285:1280-6.

442. Myler RK, Shaw RE, Stertzer SH, et al. Lesion morphology and coronary angioplasty: current experience and analysis. J Am Coll Cardiol 1992;19:1641-52.

443. Myocardial Infarction Redefined A Consensus Document of The Joint European Society of Cardiology / American College of Cardiology Committee for the Redefinition of Myocardial Infarction. J Am Coll Cardiol, 2000; 36: 959-969.

444. Nardone D, Bravette B, Shi Y, et al. Effect of microwave thermal angioplasty on intracoronary thrombus. Circulation 1991 ;84 suppl 11:11-300.

445. Narins CR, Hillegass WB Jr, Nelson CL, et al. Relation between activated clotting time during angioplasty and abrupt closure. Circulation 1996;93:667-71.

446. Narins CR, Holmes DR, Topol EJ. A call for provisional stenting: the balloon is back. Circulation, 1998; 97: 1298-305.

447. Naunheim KS, Fiore AC, Fagan DC, et al. Emergency coronary artery bypass grafting for failed angioplasty: risk factors and outcome. Ann Thorac Surg 1989;47:816-23.

448. Nesto RW, Waxman S, Mittleman MA, et al. Angioscopy of culprit coronary lesions in unstable angina: correlation of clinical presentation with plaque morphology. Am J Cardiol 1998;81:225-228.

449. Neumann FJ, et al. Prospective evaluation of hemostatic predictors of subacute stent thrombosis after coronary Palmaz-Schatz stenting. Am Coll Cardiol 1996;27(1): 15-21.

450. Neumann FJ, Walter H, Schmitt C, et al. Coronary stenting as an adjunct to direct balloon angioplasty in acute myocardial infarction. Circulation 1995;92 suppl 1:1-609.

451. Ozaki Y, Keane D, Ruygrok P, et al. Acute clinical and angiographic results with the new AVE micro coronary stent in bailout management. Am J Cardiol 1995;76:112-6.

452. Painter JA, Mintz GS, Wong SC, et al. Serial intravascular ultrasound studies fail to show evidence of chronic Palmaz-Schatz stent recoil. J Am Cardiol 1995;75:398-400.

453. Paniagua D, et al. A new score system to predict major cardiovascular events during coronary stenting. Does ACC/AHA lesion type matter? J Am Coll Cardiol 35;2:834-4.

454. Parma A, et al. The clinical, angiographic and procedural predictors of thrombosis and restenosis in Micro stent II (AVE) coronary stents. G Ital Cardiol 1998:28(11): 1238-46.

455. Parsonnet V, Fisch D, Gielchinsky I, et al. Emergency operation after failed angioplasty. J Thorac Cardiovasc Surg 1988;96:198-203.

456. Pathan A, Butte A, Harrell M, et al. Directional coronary atherectomy for the treatment of Palmaz-Schatz stent restenosis. J Am Coll Cardiol 1997;29:68A.

457. Pelletier LC, Pardini A, Renkin J, et al. Myocardial revascularization after failure of percutaneous transluminal coronary angioplasty. J Thorac Cardiovasc Surg 1985;90:265-71.

458. Pepine CJ. Coronary angiography and cardiac catheterization. In: Topol EJ, editor. Textbook of Cardiovascular Medicine. Philadelphia, PA: Lippincott-Raven, 1998:1935-56.

459. Peterson ED, Cowper PA, DeLong ER, et al. Acute and long-term cost implications of coronary stenting. J Am Coll Cardiol 1999;33:1610-8.

460. Peterson ED, Lansky AJ, Muhlbaier LH, et al. Evolving trends in angioplasty device selection: a National Cardiovascular Network (NCN) database report. J Am Coll Cardiol 1997;29:495A.

461. Phillips HR, Ohman EM, Labinaz MK, et al. Use of perfusion balloon as a primary dilation device. J Invas Cardiol 1995;7:17B-24B.

462. Phillips SJ, Kongtahworn C, Zeff RH, et al. Disrupted coronary artery caused by angioplasty: supportive and surgical considerations. Ann Thorac Surg 1989;47:880-3.

463. Piana RN, Paik GY, Moscucci M, et al. Incidence and treatment of 'no-reflow' after percutaneous coronary intervention. Circulation 1994;89:2514-8.

464. Pitney MR, Kelly SA, Allan RM, et al. Activated clotting time differential is a superior method of monitoring anticoagulation following coronary angioplasty. Cathet Cardiovasc Diagn 1996;37:145-50.

465. Pomerantz RM, Kuntz RE, Diver DJ, et al. Intracoronary verapamil for the treatment of distal microvascular coronary artery spasm following PTCA. Cathet Cardiovasc Diagn 1991;24:283-5.

466. Popma JJ, Bashore TM. Qualitative and quantitative angiographic. In: Topol EJ, editor. Textbook of Interventional cardiology. Philadelphia: W.B.Saunders 1993;1052-1068.

467. Popma JJ, et al. Predictors of early complications and "optimal" stent results after native vessel coronary stenting. Is the ACC/AHA lesion system useful in predicting outcomes. J Am Coll Cardiol 35;2:834-l.

468. Popma JJ, Leon MB, Mintz GS, et al. Results of coronary angioplasty using the transluminal extraction catheter. Am J Cardiol, 1992, 70, p. 1526-32.

469. Popma JJ, Topol EJ, Hinohara T, et al for the U.S. Directional Atherectomy Investigator Group. J Am Coll Cardiol 1992;19:1372-9.

470. Porstmann W. Ein neuer Korsett-Ballonkatheter zur trans-luminalen Rekanalisation nach Dotter unter besonderer Be-rucksichtigung von Obliterationen an den Beckenarterien. Radiol Diagn, 1973, 14, p.239-43.

471. Potkin BN, Keren G, Mintz GS, et al. Arterial responses to balloon coronary angioplasty: an intravascular ultrasound study. J Am Coll Cardiol 1992;20:942-51.

472. Pragliola C, Kootstra GJ, Lanzillo G, et al. Current results of coronary bypass surgery after failed angioplasty. J Cardiovasc Surg 1994;35:365-9.

473. Pregowski J, Kalinczuk L, Mintz GS, et al. Late stent malapposition after brachytherapy: an assessment of the incidence and mechanisms using volumetric intravascular ultrasound. J Am Coll Cardiol. 2003 ;41 (Suppl A):49A. Abstract 1128-185.

474. Preisack MB, Athanasiadis A, Voelker W, et al. Acute closure during coronary excimer laser angioplasty and conventional balloon dilatation: a comparison of management outcome and prediction. Eur Heart J 1993; J4:195-204.

475. Priestley KA, Clague JR, Buller NP, Sigwart U. First clinical experience with a new flexible low profile metallic stent and delivery system. Eur Heart J 1996;17:438-44.

476. Quigley PJ, Hinohara T, Phillips HR, et al. Myocardial protection during coronary angioplasty with an autoperfusion balloon catheter in humans. Circulation 1988;78:1128-34.

477. Raizner AE, Oesterle SN, Waksman R, et al. Inhibition of restenosis with beta-emitting radiotherapy: report of the Proliferation Reduction with Vascular Energy Trial (PREVENT). Circulation 2000; 102: 951-8.

478. Randomized placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein Ilb/IIIa blockade. The EPISTENT investigators. Lancet 1998;352(91):87-92.

479. Ray SG, Penn IM, Ricci DR, et al. Mechanism of benefit of stenting in failed PTCA. Final results from the trial of angioplasty and stents in Canada (TASC II). J Am Coll Cardiol 1995;(suppl):156A.

480. Redwood SR, Popma JJ, Kent KM, et al. "Minor" CPK-MB elevations are associated with increased late mortality following ablative new-device angioplasty in native coronary arteries. Circulation 1995;92 suppl 1:1-544.

481. Reiber JHC, Schiemanck LR, van der Zwet PMJ, et al. QCA: technical update 1995. In: de Feyter PJ, Di Mario C, Serruys PW, editors. Quantitative Coronary Imaging. Rotterdam: Barjesteh, Meeuwes & Co., 1995:9-27.

482. Reifart N, Langer A, Storger H, et al. Strecker stent as a bail-out device following percutaneous transluminal coronary angioplasty. J Intervent Cardiol 1992;5:79-83.

483. Reifart N, Vandonnael M, Krajcar M, et al. Randomized comparison of angioplasty of complex coronary lesions at a single center: Excimer Laser, Rotational Atherectomy, and Balloon Angioplasty Comparison (ERBAC) study. Circulation 1997;96:91-8.

484. Reimers B, Moussa I, Akiyama T, et al. Long-term clinical follow-up after successful repeat percutaneous intervention for stent restenosis. J Am Coll Cardiol 1997;30:186-192.

485. Reis GJ, Pomerantz RM, Jenkins RD, et al. Laser balloon angioplasty: clinical, angiographic, and histologic results. J Am Coll Cardiol 1991 ;18:193-202.

486. Resnic F, et al. Modelling the risk of major in-hospital complications following percutaneous coronary intervention. J Am Coll Cardiol 35;2:835-4.

487. Reul GJ, Cooley DA, Hallman GL, et al. Coronary artery bypass for unsuccessful percutaneous transluminal coronary angioplasty. J Thorac Cardiovasc Surg 1984;88:685-94.

488. Ribichini F, Steffenino G, Dellavalle A, et al. A plasma activity and insertion/deletion polymorphism of angiotensin I-converting enzyme: a major risk factor and a marker of risk for coronary stent restenosis. Circulation 1998;97(2):147-54.

489. Ricci DR, Buller CE, O'Neill B, et al. Coronary stent vs. prolonged perfusion balloon for failed coronary angioplasty a randomized trial. Circulation 1994;90:suppl 1:1-651.

490. Ricci DR, Ray S, Buller CE, et al. Six month follow-up of patients randomized to prolonged inflation or stent for abrupt occlusion during PTCA clinical and angiographic data: TASC II. Circulation 1995;92 suppl 1:1-475.

491. RITA Trial Participants. Coronary angioplasty versus coronary artery bypass surgery; the Randomized Intervention Treatment of Angina (RITA) trial. Lancet 1993;341:573-80.

492. Robinson КА, Roubin GS, Siegel RJ, Black AJ, Apkarian RP King SB, III. Intra-arterial stenting in the atherosclerotic rabbit. Circulation 1988;78:646-53.

493. Robinson KA, Roubin GS, Siegel RJ, et al. Intra-arterial stenting in the atherosclerotic rabbit. Circulation 1988;78:646-53.

494. Rodgers GP, Minor ST, Robinson K, et al. Adjuvant therapy for intracoronary stents: investigations in atherosclerotic swine. Circulation 1990;82:560-9.

495. Rogers C, Edelman ER. Endovascular stent design dictates experimental restenosis and thrombosis. Circulation 1995;9:2995-3001.

496. Rosenblum J, Pensabene JF, Kramer B. The TEC device: distal artherectomy and removal of an intracoronary thrombus. J Inv Cardiol 1991;3:10-2.

497. Rott D, Lawson WE, Lillis O, Dervan JP. Coronary Vasomotor Tone: Determinants and Effect on Coronary Angioplasty. J Invas Cardiol 2000;12(3):30-33.

498. Roubin GS, Cannon AD, Agrawal SK, et al. Intracoronary stenting for acute and threatened closure complicating percutaneous transluminal coronary angioplasty. Circulation 1992;85:916-27.

499. Roubin GS, Douglas JS Jr, King SB III, et al. Influence of balloon size on initial success, acute complications, and restenosis after percutaneous transluminal coronary angiplasty. A prospective randomized study. Circulation 1988;78:557-65.

500. Rowe MH, Hinohara T, White NW, et al. Comparison of dissection rates and angiographic results following directional coronary atherectomy and coronary angioplasty. Am J Cardiol 1990;66:49-53.

501. Royer T, Guyon P, Glatt В et al. Treatment of in-stent restenosis: result of a pilot randomized study beetween balloon and cutting balloon. Am J Cardiol 1998;suppl:TCT:192.

502. Ruygrok PN, De Jaegere PP, Verploegh JJ, et al. Immediate outcome following coronary angioplasty. A contemporary single centre audit. Eur Heart J 1995;16:24-9.

503. Ryan TJ, Axon DP, Gunnar RM, et al. Guidelines for percutaneous transluminal coronary angioplasty A report of the ACC/AHA task force on assessment of diagnostic and therapeutic cardiovascular procedures. J Am Coll Cardiol 1988;12:529-45.

504. Sabate M, Costa MA, Kozuman K, et al. Geographic miss: a cause of treatment failure in radio-oncology applied to intracoronary radiation therapy. Circulation 2000;103:E65-6.

505. Saenz CB, Schwartz KM, Slysh SJ, et al. Experience with the use of coronary autoperfusion catheter during complicated angioplasty. Cather Cardiovasc Diagn 1990;20:276-8.

506. Saito S, Arai H, Kim K, et al. Initial experience of unipolar radiofrequency hot balloon angioplasty for bail-out from abrupt coronary closure after conventional balloon angioplasty. J Am Coll Cardiol 1993;21(suppl A):338A.

507. Saito S, Kim K, Hosokawa G, et al. Primary Palmaz-Schatz stent implantation without Coumadin in acute myocardial infarction. Circulation 1995;92:I:796.

508. Sanders M. Angiographic changes thirty minutes following percutaneous transluminal coronary angioplasty. Angiology 1985;36:419-24.

509. Santiago FS, Khachigian LM. Evolution of nucleic acids as genespecific targeting agents. J Mol Med. In Press.

510. Santiago FS, Lowe HC, Kavurma MM, et al. Novel DNA enzyme targeting NGFI-A mRNA inhibits vascular smooth muscle proliferation and regrowth after injury. Nature Med 1999;11:1264.

511. Santiago FS, Lowe HC, Kavurma MM, et al. Novel DNA enzyme targeting NGFI-A mRNA inhibits vascular smooth muscle proliferation and regrowth after injury. Nature Med 1999; 11:1264.

512. Sarembock IJ, Gertz SD, Gimple LW, et al. Effectiveness of recombinant desulphatohirudin in reducing restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits. Circulation 1991;84:232-43.

513. SAS PROCedure GENMOD version 6.12. Models for longitudinal data: a generalized estimating equation approach. Biometrics 1988;44:1049-60.

514. Savas V, Puchrowicz S, Williams L, et al. Angioplasty outcome using long balloons in high-risk lesions. J Am Coll Cardiol 1992;19:34A.

515. Schiele F, Meneveau N, Vuillemenot A, et al. Intracoronary ultrasound assessment of balloon angioplasty in intrastent restenosis. J Am Coll Cardiol 1997;29:240A.

516. Schiele F, Meneveau N, Vuillemenot A, et al. Rotational atherectomy followed by balloon angioplasty for treatment of restenosis in coronary stents. J Am Coll Cardiol 1997;29:498A.

517. Schiele F, Meneveau N, Vuillemenot A, et al. Treatment of in-stent restenosis with high speed rotational atherectomy and IVUS guidance in small <3.0 mm vessels. Cathet Cardiovasc Diagn. 1998; 44:77-82.

518. Schieman G, Cohen BM, Kozina J, et al. Intracoronary urokinase for intracoronary thrombus accumulation complicating percutaneous transluminal coronary angioplasty in acute ischemic syndromes. Circulation 1990;82:2052-60.

519. Schomig A, Kastrati A, Mudra H, et al. Four-year experience with Palmaz-Schatz stenting in coronary angioplasty complicated by dissection with threatened or present vessel closure. Circulation 1994;90:2716-24.

520. Schomig A, Neumann FJ, Kastrati A, et al. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary artery stents. N Engl J Med 1996;334:1084-1089.

521. Schuhlen H, Kastrati A, Mehili J, et al. Evaluation of the BiodivYsio stent with matrix HI coating designed for local drug delivery in coronary arteries: a randomized trial. J Am Coll Cardiol. 2003;41 (Suppl A):7A.

522. Schwartz L, Andrus S, Sinclair IN, et al. Restenosis following laser balloon coronary angioplasty: results of a randomized pilot multicenter trial. Circulation 1991;84:suppl 11:11-361.

523. Schwartz L, Bourassa MG, Lesperence J, et al. Aspirin and dipyridamole in the prevention of restenosis after percutaneous transluminal coronary angioplasty. N Engl J Med 1998;318:1714-9.

524. Schwartz RS, Huber КС, Murphy JG, et al. Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model. J Am Coll Cardiol 1992;19:267-74.

525. Schwartz RS, Murphy JG, Edwards WD, et al. Restenosis after balloon angioplasty: a practical proliferative model in porcine coronary arteries. Circulation 1990;82:2190-200.

526. Schwartz RS. Animal models of human coronary restenosis. In Topol EJ, ed. Textbook of Interventional Cardiology. 2nd ed. Philadelphia, PA: W.B.Saunders 1994;365-81.

527. Scott N, Weintraub WS, Carlin SF, et al. Recent changes in the management and outcome of acute closure after percutaneous transluminal coronary angioplasty. Am J Cardiol 1993;71:1159-63.

528. Seggewiss H, Gleichmann U, Fassbender D, et al. Therapy for acute vascular complications in percutaneous transluminal coronary angioplasty with the autoperfusion balloon catheter. Eur Heart J 1992;13:1649-57.

529. Sercelik A, Batyraliev ТА, Samko AN, et al. In-stent restenosis after placement of various coronary stent types. Материалы Первого Российского Съезда Интервенционных Кардиоангиологов, Москва 2002;83-84.

530. Serruys PW, de Jaegere P, Kiemeneij F, et al. A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease: Benestent Study Group. N Engl J Med 1994;331:489-495.

531. Serruys PW, Emanuelsson H, van der Giessen W, et al. Heparincoated Palmaz-Schatz stents in human coronary arteries: early outcome of the BENESTENT-II pilot study. Circulation 1996;93:412-22.

532. Serruys PW, Kay IP. I like the candy, I hate the wrapper. Circulation 2000;101:3-7.

533. Serruys PW, Keane D. The bailout stent: is a friend in need always a friend indeed? Circulation 1993;88:2455-7.

534. Serruys PW, Klein W, Tijssen JP, et al. Evaluation of ketanserin in the prevention of restenosis after percutaneous transluminal coronary angioplasty: a multicenter randomized double-blind placebo-controlled trial. Circulation 1993;88:1588-601.

535. Serruys PW, Kutryk MJB, Bruining N, et al. Antisense oligonucleotide against c-myc administered with the transport catheter for the prevention of in-stent restenosis: results of the randomised ITALICS trial. Circulation 1998;98:I1909.

536. Serruys PW, Kutryk MJB. Handbook of Coronary Stents. 3rd ed. London: Martin Dunitz 2000.

537. Serruys PW, Lujiten HE, Beatt KJ, et al. Incidence of restenosis after successful coronary angioplasty: A time related fenomenon. Circulation 1988;77:361-71.

538. Serruys PW, Rensing BJ, Hermans LURM, Beatt KJ. Definition of restenosis after coronary angioplasty: a quickly envolving concept. J Invest Cardiol 1989;4:265-76.

539. Serruys PW, van der Giessen W, Garcia E, et al. Clinical and angiographic results with the Multi-Link stent implanted under intravascular ultrasound guidance (WEST-2 study). J Invasive Cardiol 1998; 10 Suppl B:20B-27B.

540. Serruys PW, van Hout B, Bonnier H, et al. Randomised comparison of implantation of heparin-coated stents with balloon angioplasty in selected patients with coronary artery disease (BENESTENT II). Lancet 1998;352:673-81.

541. Serruys PW. Herrman JP, Simon R, et al for the Helvetica Investigators. A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. N Engl J Med 1995;333:757-63.

542. Shadoff N for the International Primary Perfusion Registry and the New Mexico Heart Institute. J Invas Cardiol 1995;7:25B-31B.

543. Sharma GV, Lapsley D, Vita JA, et al. Usefulness and tolerability of hirulog, a direct thrombin-inhibitor, in unstable angina pectoris. Am J Cardiol 1993;72:1357-60.

544. Sharma SK, Duvvuri S, Dangas G, et al. Rotational atherectomy for in-stent restenosis: acute and long-term results of the first 100 cases. J Am Coll Cardiol 1998;32:1358-65.

545. Sharma SK, et al, Clinical, angiographic, and procedural determinants of major and minor coronary dissection during angioplasty. Am Heart J 1993;126:39-47.

546. Sharma SK, Kini A, King T, et al. Randomised Trial of Rotational Atherectomy versus Balloon Angioplasty for In-Stent Restenosis (ROSTER): interim analysis of 150 cases. Eur Heart J 1999;20:281A.

547. Sharma SK, Rajawat Y, Kakarala V, et al. Angiographic pattern of in-stent restenosis after Palmaz-Schatz stent restenosis. J Am Coll Cardiol 1997;29:313A.

548. Shawl FA, Dougherty KG, Hoff SB. Does inflation strategy influence acute outcome and long term results? Circulation 1993;88:I587.

549. Sheppard R, Eisenberg MJ. Intracoronary radiotherapy for restenosis. N Engl J Med 2001;344:295-7.

550. Shiran A, Mintz GS, Waksman R, et al. Early lumen loss after treatment of in-stent restenosis. An intravascular ultrasound study. Circulation 1998;98:200-203.

551. Sigwart U, Puel J, MirKovitch V, et al. Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty. N Engl J Med 1987;316:701-706.

552. Sigwart U, Urban P, Golf S, et al. Emergency stenting for acute occlusion after coronary balloon angioplasty. Circulation 1988;78:1121-7.

553. Silber S, Brockhoff C, Dorr R, et al. The German IST-registry: need of one year of clopidogrel to avoid late stent thrombosis. J Am Coll Cardiol 2001;37:82A.

554. Simmonton CA. Lesion-specific technique considerations in directional coronary atherectomy. Cathet Cardiovasc Diagn 1993;(suppl l):3-9.

555. Simons M, Edelman ER, DeKeyser JL, et al. Antisense c-myb oligonucleotides inhibit intimal smooth muscle cell accumulation in vivo. Nature 1992;359:67-73.

556. Simonton CA, Kowalchuk GJ, Austin WK. Preservation of regional myocardial function during coronary angioplasty with an autoperfusion balloon catheter: a case report. Cathet Cardiovasc Diagn 1991;22:28-34.

557. Simoons ML, de Boer MJ, van den Brand MJ, et al and the European Cooperative Study Group. Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina. Circulation 1994;89:596-603.

558. Simpfendorfer C, Belardi J, Ballamy G, et al. Frequency management, and follow-up of patients with acute coronary occlusions after percutaneous transluminal coronary angioplasty. Am J Cardiol, 1987, 59, p.267-269.

559. Sinclair IN, McCabe CH, Sipperly ME, Baim DS. Predictors, therapeutic options, and long-term outcome of abrupt reclosure. Am J Cardiol 1988;61:Suppl G:61G.

560. Singh M, Holmes DR, Grill DE, Rihal CS. Angiographic and procedural failure after percutaneous coronary intervention: Mayo Clinic Experience. // Am J Cardiol 1999;84(suppl 6A):75P.

561. Sirnes PA, Golf S, Myreng Y, et al. Stenting In Chronic Coronary Occlusion (SICCO): a randomised, controlled trial of adding stent implantation after successful angioplasty. J Am Coll Cardiol 1996;28:1444-51.

562. Smith SC, Dove JT, Jacobs AK, et al. ACC/AHA Guidelines for Percutaneous Coronary Intervention (Revision of the 1993 PTCA Guidelines). A Report of the ACC/AHA Task Force on Practice Guidelines. // J Am Coll Cardiol, 2001; 37: 2239i-lxvi.

563. Smucker ML, Sarnat WS, Kil D, et al. Salvage from cardiogenic shock by atherectomy after failed emergency coronary artery angioplasty. Cathet Cardiovasc Diagn 1990;21:23-5.

564. Sones FM Jr. Coronary arteriography. Read before the Eighth Annual Convention of the American College of Cardiology, Philadelphia, 1959.

565. Sousa JE, Costa MA, Abizaid AC, et al. Sustained suppression of neointimal proliferation by sirolimus-eluting stents: one-year angiographic and intravascular ultrasound follow-up. Circulation. 2001;104:2007-2011.

566. Spears JR, Reyes VP, Wynne J, et al. Percutaneous coronary laser balloon angioplasty: initial results of a multicenter experience. J Am Coll Cardiol 1990;16:293-303.

567. Spears JR, Safian RD, Douglas JS, et al and the LBA Study Group. Multicenter acute and chronic results of laser balloon angioplasty for refractory abrupt closure after PTCA. Circulation 1991 ;84 suppl 11:11-517.

568. Stack RS, Quigley PT, Collins G, Phillips HR III. Perfusion balloon catheter. Am J Cardiol 1988;61:77G-80G.

569. Stauffer JC, Eeckhout E, Vogt P, et al. Stand-by versus stent-by during percutaneous transluminal coronary angioplasty. Am Heart J 1995;130:21-6.

570. Steele PM, Chesebro JH, Stanson AW, et al. Balloon angioplasty: natural history of the pathophysiological response to injury in a pig model. Circ Res 1985;57:105-12.

571. Stefanadis C, Diamantopoulos L, Vlachopoulos C, et al. Thermal heterogeneity within human atherosclerotic coronary arteries detected in vivo: a new method of detection by application of a special thermography catheter. Circulation 1999;99:1965-1971.

572. Stein B, Weintraub WS, Gebhart SP, et al. Influence of diabetes mellitus on early and late outcomes after percutaneous transluminal coronary angioplasty. Circulation 1995;91:979-89.

573. Stertzer SH, Pomerantsev EV, Shaw RE, et al. Comparative study of the angiographic morphology of coronary artery lesions treated with PTCA, directional coronary atherectomy, or high speed rotational ablation. Cathet Cardiovasc Diagn 1994;33:1-9.

574. Strauss В, Umans V, Van Suylen RJ, et al. Directional atherectomy for treatment of restenosis within coronary stents: clinical, angiographic and histologic results. J Am Coll Cardiol 1992;20:1465-73.

575. Strauss BH, Serruys PW. The coronary wallstent. In Topol EJ, editor. Textbook of interventional cardiology. 2nd ed. Philadelphia W.B.Saunders 1994;687-701.

576. Strauss BH, Umans VA, van Suylen RJ, et al. Directional atherectomy for treatment of restenosis within coronary stents: clinical, angiographic and histologic results. J Am Coll Cardiol 1992;20:1465-1473.

577. Sunamura M, di Mario C, Piek JJ, et al. Cyclic flow variations after angioplasty: a raare phenomenon predictive of immediate complications. DEBATE Investigator's Group. Am Heart J 1996;131:843-8.

578. Sundram P, Harvey JR, Johnson RG, et al. Benefit of the perfusion catheter for emergency coronary artery grafting after failed percutaneous transluminal coronary angioplasty. Am J Cardiol 1989;63:282-5.

579. Suryapranata H, Boland JL, Pieper M, et al. Clinical and angiographic results with the beStent. Int J Cardiovasc Intervent 2000;3:21- 8.

580. Sutton JM, Ellis SG, Roubin GS, et al for the Gianturco-Roubin Intracoronary Stent Investigator Group. Circulation 1994;89:1126-37.

581. Suzuki T, Kopia G, Hayashi S, et al. Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. Circulation 2001;104:1188-1193.

582. Tahk S-J, Yoon M-H, Choi S-Y, et al. The effect of microvascular dysfunction on the relationship between fractional flow reserve and anatomic stenosis severity. J Am Coll Cardiol. 2003;41(Suppl A):8A.

583. Takagi T, Akasaka T, Yamamuro A, et al. Troglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with noninsulin dependent diabetes mellitus. J Am Coll Cardiol 2000;36:1529-35.

584. Talley JD, Weintraub WS, Roubin GS, et al. Failed elective percutaneous transluminal coronary angioplasty requiring coronary artery bypass surgery: in-hospital and late clinical outcome at 5 years. Circulation 1990;82:1203-13.

585. Tan K, Sulke N, Taub N, Sowton E. Clinical and lesion morphologic determinants of coronary angioplasty success and complications: current experience. J Am Coll Cardiol. 1995;25:855-65.

586. Tanabe K, Lemos PA, Lee C-H, et al. The impact of sirolimus-eluting stents on the outcome of patients with bifurcation lesions. J Am Coll Cardiol. 2003;41(Suppl A):12A.

587. Tanajura LF, Abizaid AA, Feres F, et al. Randomized intravascular ultrasound comparison between patients that underwent amorphous hydrogenated silicon-carbide coated stent deployment versus uncoated stents. J Am Coll Cardiol. 2003;41(Suppl A):58A.

588. Tani S, Wantanabe I, Oguchi S, et al. Lipid-lowering therapy with pravastatin reduces coronary plaque volume: role of high-density lipoprotein cholesterol containing apolipoprotein A-l. J Am Coll Cardiol. 2003;41(Suppl A):296A.

589. Tebbe U, Carlsson J, Mikefe S, et al. Results and outcome of percutaneous transluminal coronary angioplasty in hospitals with and without on-site surgical backup. // Eur J Cardiol 1997;8:476.

590. Teicholz LE, Kreulen T, Herman MV, Gorlin R. Problems in echocardiography volume determinations: Echocardiographic-angiographic correlations in presence or absence of asynergy. Am J Cardiol 1976;37:7.

591. Teirstein PS, Massullo V, Jani S, et al. A double-blinded randomized trial of catheter based radiotherapy to inhibit restenosis after coronary stenting. N Engl J Med 1997;336:1697-1703.

592. Teirstein PS, Massullo V, Jani S, et al. Catheter-based radiotherapy to inhibit restenosis after coronary stenting. N Engl J Med 1997;336:1697-703.

593. Teirstein PS, Massullo V, Jani S, et al. Three-year clinical and angiographic follow-up after intracoronary radiation: results of a randomised clinical trial. Circulation 2000;101:360-5.

594. Teirstein PS, Schatz RA, DeNardo SJ, et al. Angioscopic versus angiographic detection of thrombus during coronary interventional procedures. Am J Cardiol 1995;75:1083-1087.

595. Teirstein PS, Vogel RA, Dorros G, et al. Prophylactic versus standby cardiopulmonary support for high-risk percutaneous transluminal coronary angioplasty. // J Am Coll Cardiol 1993;21:590-6.

596. Teirstein PS, Warth DC, Haq N, et al. High speed rotational coronary atherectomy for patients with diffuse coronary artery disease. J Am Coll Cardiol 1991;18:1694-701.

597. Teirstein PS. Beta-radiation to reduce restenosis: Too little, too soon? Circulation 1997;95:1095-7.

598. Tenaglia AN, Buller CE, Kisslo КБ, et al. Mechanisms of balloon angioplasty and directional coronary atherectomy as assessed by intracoronary ultrasound. J Am Coll Cardiol 1992;20:685-91.

599. Tenaglia AN, Fortin DF, Califf RM, et al. Predicting the risk of abrupt vessel closure after angioplasty in an individual patient. J Am Coll Cardiol 1994;24:1004-11.

600. Tenaglia AN, Quigley PJ, Kereiakes DJ, et al. Coronary angioplasty performed with gradual and prolonged inflation using a perfusion balloon catheter: procedural success and restenosis rate. Am Heart J 1992;124:585-9.

601. Ternovoy S, Sinitsyn V, Batyraliev T. Electron-beam and spiral computed tomography of heart and great vessels. Coronary angiography. Istanbul 2001;102-11.

602. The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein Ilb/IIIa receptor in high-risk coronary angioplasty. The EPIC Investigation. N Engl J Med 1994;330:956-61.

603. The TIMI IIIB Investigators. Effect of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction. Results of the TIMI IIIB Trial. Circulation 1994;89:545-56.

604. Till FV, Aliabadi D, Kinn JW, et al. Real life stenting: a comparison of target vessel revascularization in Benestent-stress lesions to non-Benestent-stress lesions. Circulation 1996;94:I332.

605. TIMI Study Group. The thrombolysis in myocardial infarction trial. N Engl J Med 1985;312:932-936.

606. Topaz O, Vetrovec GW. The stenotic stent: mechanisms and revascularization options. Cathet Cardiovasc Diagn 1996;37:293-299.

607. Topol EJ, Leya F, Pinkerton CA, et al. for the CAVEAT Study Group. A comparison of directional atherectomy with coronary angioplasty in patients with coronary artery disease. N Engl J Med 1993;329:221-227.

608. Turi ZG, Campbell CA, Gottimukkala MV, Kloner RA. Preservation of distal coronary perfusion during prolonged balloon inflation with an autoperfusion angioplasty catheter. Circulation 1987;75:1273-80.

609. Uemura R, Yamamoto E, Tokita Y, et al. Impact of plaque composition on arterial remodeling: comparison between atherectomy tissue and intravascular ultrasound. J Am Coll Cardiol. 2003 ;41 (Suppl A):41A. Abstract 1102-180.

610. Umans VAWM, deFeyter PJ, Deckers JW, et al. Acute and long-term outcome of directional coronary atherectomy for stable and unstable angina. Am J Cardiol 1994;74:641-6.

611. Uretsky BF, Denys BG, Counihan PC, Ragosta M. Angioscopic evaluation of incompletely obstructing coronary intraluminal filling defects: comparison to angiography. Catheter Cardiovasc Diag 1994;33:323-329.

612. Vaitkus PT, Herrmann HC, Laskey WK. Management and immediate outcome of patients with intracoronary thrombus during percutaneous transluminal coronary angioplasty. Am Heart J 1992;124:1-8.

613. Van Tassel RA, Gobel FL, RydeU MA, et al. A less traumatic catheter for coronary arteriography. Cathet Cardiovasc Diagn 1985;11:187-99.

614. Vandergoten P, Brosens M, Benit E. Coronary aneurysm five months after intracoronary beta-irradiation. Acta Cardiol 2000;55:313-5.

615. Vandormael M, Reifart N, Preusler W, et al. Comparison of excimer laser angioplasty and rotational atherectomy with ballon angioplasty for complex lesions: ERBAC study final results. J Am Coll Cardiol 1994:57A.

616. Velianou J, et al. Abciximab reduces early mortality but not late adverse outcomes in unselected diabetics undergoing stent implantation. J Am Coll Cardiol 2000;35:2:1086-87.

617. Verheye S, Salame MY, Robinson KA, et al. Short- and long-term histopathologic evaluation of stenting using a self-expanding nitinol stent in pig carotid and iliac arteries. Cathet Cardiovasc Diagn 1999;48:316-23.

618. Verin V, Popowski Y, de Bruyne B, et al. Endoluminal beta-radiation therapy for the prevention of coronary restenosis after balloon angioplasty. N Engl J Med 2001;344:243-9.

619. Verna E, Repett S, Boscarini M, et al. Management of complicated coronary angioplasty by intracoronary urokinase and immediate reangioplasty. Cathet Cardiovasc Diagn 1990;19:116-22.

620. Versaci F, Gaspardone A, Tomai F, et al. A comparison of coronary artery stenting with angioplasty for isolated stenosis of the proximal left anterior descending coronary artery. N Engl J Med 1997;336:817.

621. Vesselinovich D. Animal models and the study of atherosclerosis. Arch Pathol Lab Med 1988;112:1011-7.

622. Vetter JW, Robertson GC, Selmon MR, et al. Use of directional coronary atherectomy for failed PTCA. Circulation 1992;86 suppl 1:1-249.

623. Violaris AG, Melkert R, Serruys PW. Influence of serum cholesterol and cholesterol subtractions on restenosis after successful coronary angioplasty: a quantitative angiographic analysis of 3,336 lesions. Circulation 1994;90:2267-79.

624. Virmani R, Farb A. Pathology of in-stent restenosis. Curr Opin Lipidol 1999;10:499-506.

625. Vlietstra RE, Holmes DR Jr, Smith HC, et al. Percutaneous transluminal coronary angioplasty: initial Mayo Clinic experience. Mayo Clin Proc 1981;56:287-293.

626. Vrolix M, Piessens J for the European Wiktor Stent Study Group. Usefulness of the Wiktor stent for treatment of threatened or acute closure complicating coronary angioplasty. Am J Cardiol 1994;73:737-41.

627. Wahl MR, Higano ST, Lerman A. Intravascular ultrasound-derived coronary flow reserve. J Am Coll Cardiol. 2003;41(Suppl A):28A. Abstract 1077-175.

628. Waksman R, Bhargava B, Saucedo JF, et al. Yttrium-90 delivered via a centering catheter and afterloader, given both before and after stent implantation, inhibits neointima formation in porcine coronary arteries. Cardiovasc Radiat Med 2000;2:11-7.

629. Waksman R, Bhargava B, Taafe M, et al. Prolonged antiplatelet therapy to reduce late thrombosis after intracoronary gamma radiation in patients with in-stent restenosis: "plavix-WRIST". Circulation 2000; 102:11570.

630. Waksman R, Ghazzal ZM, Baim DS, et al. Myocardial infarction as a complication of new interventional devices. Am J Cardiol 1996;78:751-6.

631. Waksman R, Serruys PW. Handbook of Vascular Brachytherapy. 1st ed. London: Martin Dunitz Ltd. 1998.

632. Waksman R, White RL, Chan RC, et al. Intracoronary gammaradiation therapy after angioplasty inhibits recurrence of in-patients with in-stent restenosis. Circulation 2000; 101:2165-71.

633. Waksman R. Late thrombosis after radiation: sitting on a time bomb. Circulation 1999;100:780-2.

634. Waller BF. Morphologic Aspects of Balloon Angioplasty and Related Procedures. Rev Port Cardiol 1999;18:Suppl 1:13-9.

635. Walton AS, Oesterle SN, Yeung AC. Coronary artery stenting for acute closure complicating primary angioplasty for acute myocardial infarction. Cather Cardiovasc Diagn 1995;34:142-6.

636. Warner M, Chami Y, Johnson D, Cowley MJ. Directional coronary atheterectomy for failed angioplasty due to occlusive coronary dissection. Cathet Cardiovasc Diagn 1991;24:28-31.

637. Warth DC, Leon MB, O'Neill W, et al. Rotational atherectomy multicenter registry: acute results, complications and 6 month angiographic follow-up in 709 patients. J Am Coll Cardiol 1994;24:641-8.

638. Waxman S, Mittleman MA, Zarich SW, et al. Angioscopic assessment of coronary lesions underlying thrombus. Am J Cardiol 1997;79:1106—1109.

639. Waxman S, Mittleman MA, Zarich SW, et al. Plaque Disruption and Thrombus in Ambrose's Angiographic Coronary Lesion Types. Am J Cardiol 2003;92:16-20.

640. Waxman S, Sassower MA, Mittleman MA, et al. Angioscopic predictors of early adverse outcome after coronary angioplasty in patients with unstable angina and non-Q wave myocardial infarction. Circulation 1996;93:2106-2113.

641. Webb JG, Abel JG, Allard MF, et al. AVE microstent: initial human experience. Circulation 1994;90 suppl 1:1-612.

642. Webb JG, Myler RK, Shaw RE, et al Coronary angioplasty in young adults: initial results and late outcome. J Am Coll Cardiol 1990;16:1341-7.

643. Wehinger A, et al. Lipoprotein(a) and coronary thrombosis and restenosis after stent placement. J Am Coll Cardiol 1999;33(4): 1005-12.

644. Weinberger J, Amols H, Ennis RD, et al. Intracoronary irradiation: dose response for the prevention of restenosis in swine. Int J Radiat Oncol Biol Phys 1996;36: 767-75.

645. Weintraub WS, Kosinski AS, Brown CL, King SB III. Can restenosis after coronary angioplasty be predicted from clinical variables? J Am Coll Cardiol 1993;21:6-14.

646. Whisenant BK, Baim DS, Kuntz RE, et al. Rheolytic thrombectomy with the Possis AngioJet: technical considerations and initial clinical experience. J Invasive Cardiol 1999;11:421-6.

647. White CJ, Ramee SR, Collins TJ, Escobar AE, Karsan A, Shaw D, Jain SP, Bass ТА, Heuser RH, Teirstein PS, et al. Coronary thrombi increase PTCA risk. Angioscopy as a clinical tool. Circulation 1996;93:253-258.

648. Whitlow PL, de Jaegere PP, Serruys PW. The Wiktor stent. In Topol EJ, editor. Textbook of interventional cardiology. 2nd ed. Philadelphia; W.B.Saunders 1994;727-41.

649. Whitlow PL, Robertson GC, Rowe MH, et al. Directional coronary atherectomy for failed percutaneous transluminal coronary angioplasty. Circulation 1990;82 suppl 111:1.

650. Wiemy L, Plass R, Porstmann W. Long-term results in 100 consecutive patients treated by transluminal angioplasty. Radiology 1974; 12:543.

651. Williams DO, Joelson JM, Most AS. Angiographic findings when chest pain reoccurs after successful percutaneous transluminal coronary angioplasty. Am J Cardiol 1987;60:792-5.

652. Wilson SH, et al. Timing of coronary stent thrombosis in patients treated with ticlopidine and aspirin. Am J Cardiol 1999;83(7): 1006-11.

653. Wolf A, Schwarz F, Hofmann M, et al. Repetitive Balloon angioplasty for Recurrent In-Stent Restenosis: Results of First and Second PICA in Focal and Diffuse Stenosis. J Am Coll Cardiol 1999;suppl(l): 1037-51

654. Wolfe MW, Roubin GS, Schweiger M, et al. Length of hospital stay and complications after percutaneous transluminal coronary angioplasty. Clinical and procedural predictors. Heparin Registry Investigators. Circulation 1995;92:311-9.

655. Wong SC, Hong MK, Chuang YC, et al. The Anti-Platelet Treatment After Intravascular Ultrasound Guided Optimal Stent Expansion (APLAUSE) Trial. Circulation 1995;92 suppl 1:1-795.

656. Yamahita K, Satake S, Ohira H, Ohtomo K. Radiofrequency thermal balloon coronary angioplasty: a new device for successful percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 1994;23:336-40.

657. Yamamoto K, Morishita R, Tomita N, et al. Ribozyme oligonucleotides against transforming growth factor-B inhibited neointimal formation after vascular injury in the rat model. Circulation 2000;102:1308-14.

658. Yock CA, Boothroyd DB, Owens DK, et al. Projected Long-Term Costs of Coronary Stenting in Multivessel Coronary Disease Based on the Experience of the Bypass Angioplasty Revascularization Investigation (BARI). Am Heart J 2000;14:556-64.

659. Yokoi H, Kimura T, Nakagawa Y, et al. Long-term clinical and quantitative angiographic follow-up after the Palmaz-Schatz stent restenosis. J Am Coll Cardiol 1996;27:224A.

660. Yokoi H, Tamura T, Kimura T, et al. Clinical and angiographic predictors of diffuse type in-stent restenosis. J Am Coll Cardiol 1998;SupplA: 1060-80

661. Zalewski A, Berry C, Kosman ZK, et al. Myocardial protection with autoperfusion during prolonged coronary artery occlusion. Am Heart J 1990;119:41-6.

662. Zapolanski A, Rosenblum J, Myler RK, Shaw RE, Stertzer SH, Millhouse FG, et al. Emergency coronary artery bypass surgery following failed balloon angioplasty: role of the internal mammary artery graft. J Cardiol Surg 1991;6:439-48.

663. Zeitler E, Schoop W, Zahnow W. The treatment of occlusive arterial disease by transluminal catheter angioplasty. Radiology 1971;99:19-26.

664. Zueco J, Bethencourt A, Pasalodos J, et al. Implantacio en electiva de stent versus angioplastia con balon en el tratamiento de la reestenosis intrastent.

665. Diseno у datos preliminares de un estudio multicentrico у randomizado (RIBS). Rev Esp Cardiol 1998;51 (suppl 5): 16.